UScholar Works
 
Filters: Date: "1993" Department: "Neurosurgery" Collection: "ir_uspace" Type: "Text"
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1 Couldwell, William T.Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifenPREVIOUS WORK HAS demonstrated the importance of the Protein Kinase C (PKC) signal transduction system in regulating the growth rate of malignant gliomas in vitro. Tamoxifen inhibits PKC in a minority of malignant gliomas within the micromolar concentration range in vitro, a property distinct from...Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Chemotherapy; Glioma1993
2 Couldwell, William T.Cosmetic mastoidectomy for the combined supra/infratentorial transtemporal approachThe authors describe a cosmetic mastoidectomy technique for use when performing a combined supra/ infratentorial craniotomy and transtemporal exposure. The technique involves a single temporal suboccipital bone flap and cosmetic mastoidectomy, removing the outer table of bone for later replacement...Surgical approach; Supratentorial approach; Infratentorial approach; Petroclival meningiomas1993
3 Couldwell, William T.Development of neurosurgery in Southern California and the Los Angeles County/University of Southern California Medical CenterThe Los Angeles County General Hospital has played an integral role in the development of medicine and neurosurgery in Southern California. From its fledgling beginnings, the University of Southern California School of Medicine has been closely affiliated with the hospital, providing the predomina...Historical vignette; Los Angeles County General Hospital; University of Southern California School of Medicine; Neurosurgical history1993
4 Dailey, Andrew T.Emergent aneurysm clipping without angiography in the moribund patient with intracerebral hemorrhage: the use of infusion computed tomography scansTHE AUTHORS REPORT their experience with 25 patients (mean age, 44.3 ± 12.1 years) with an intracerebral hematoma (ICH) from a ruptured aneurysm who were emergently operated on without angiography. Instead, preoperative high-resolution infusion computed tomography (CT) scans were used to identify...Ruptured aneurysms; Computed tomography; Infusion computed tomography; Aneurysm clipping1993
5 Couldwell, William T.Life-threatening reactions to propofolTo the Editor: Propofol (2,6-diisopropyl phenol; Diprivan; Stuart Pharmaceuticals, Wilmington, DE) has been advocated as a titratable continuous infusion anesthetic agent associated with fast and smooth recovery (2, 7). The anesthetic properties of a smooth induction, short half-life, and rapid eme...Propofol; Diprivan1993
6 Kestle, John R. W.Moyamoya phenomenon after radiation for optic gliomaThe role of radiotherapy in the management of patients with optic pathway glioma is controversial. In a series of patients with optic pathway glioma treated at The Hospital for Sick Children in Toronto, five children were encountered who developed moyamoya phenomenon after radiotherapy. A retrospec...Optic pathway glioma1993
7 Dailey, Andrew T.Paragangliomas of the sellar region: report of two casesTWO CASES OF paraganglioma arising from the parasellar region are presented. Both occurred in middle-aged women who sought treatment of headaches but who had no endocrinological dysfunction; one case was associated with ophthalmoplegia from cavernous sinus involvement. Diagnosis in both cases was ...Paragangliomas; Sellar region; Parasellar region; Chemodectoma; Pituitary tumor1993
8 Couldwell, William T.Penetrating craniocerebral injury resultant from gunshot wounds: gang-related injury in children and adolescentsWE PROSPECTIVELY AND retrospectively reviewed a series of 780 patients who presented to the University of Southern California/Los Angeles County Medical Center with a diagnosis of gunshot wound to the brain during an 8-year period. Of these, 105 were children ranging in age from 6 months to 17 yea...Craniocerebral injury; Los Angeles County General Hospital; University of Southern California School of Medicine1993
9 Couldwell, William T.Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. a comparison between staurosporine and tamoxifenWE HAVE PREVIOUSLY demonstrated that the proliferation of established human glioma cell lines correlated with protein kinase C (PKC) activity and that a relatively selective PKC inhibitor, staurosporine, inhibits glioma cell proliferation. The purpose of this study was to determine whether low-passa...Staurosporin; Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Glioma cell lines1993
10 Dailey, Andrew T.Resolution of an actinomycotic abscess with nonsurgical treatment: case reportA CASE OF actinomycotic brain abscess is presented. Conservative treatment by prolonged administration of antibiotics after needle biopsy showed complete resolution of the abscess. Previously reported cases suggest that definitive treatment requires excision or open surgical drainage of the abscess...Actinomycotic abscess; Brain abscess; Actinomyces israelii; Nonsurgical treatment1993
11 Kestle, John R. W.Role of angiography following aneurysm surgeryThe postoperative angiograms in 66 patients who underwent craniotomy for clipping of 78 cerebral aneurysms were reviewed. Indications for urgent postoperative angiography included neurological deficit or repeat subarachnoid hemorrhage. Routine postoperative angiograms were carried out in the remai...Postoperative angiography; Aneurysm rest; Cerebral angiography; Vascular occlusion1993
12 Schmidt, Meic H.Role of photodynamic therapy in posterior fossa brain tumors: a preclinical study in a canine glioma modelPhotodynamic therapy was studied in dogs with and without posterior fossa glioblastomas. This mode of therapy consisted of intravenous administration of Photofrin-II at doses ranging from 0.75 to 4 mg/kg 24 hours prior to laser light irradiation in the posterior fossa. Tissue levels of Photofrin-l...Brain neoplasm; Posterior fossa; Photodynamic therapy; Glioblastomas; Dog; Photofrin-II; Canine glioma model1993
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