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1 Couldwell, William T.Definition of the role of contemporary surgical management in cisternal and parenchymatous cysticercosis cerebriWith increasing immigration from endemic regions, the incidence of neurocysticercosis in North America is rising. This retrospective study was undertaken to examine the role of surgery in those cases presenting with large cystic parenchymal and cisternal lesions in the current era of anthelminthic a...Brain cyst; Computed tomography; Neurocysticercosis; Magnetic resonance imaging; Praziquantel; Stereotaxis1991
2 Couldwell, William T.Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitroDirect measurement of protein kinase C (PKC) activity in vitro revealed a significant increase in the activity of the enzyme in all human malignant glioma lines examined and the rat C6 tumor in comparison with control nonneoplastic astrocyte and mixed glial cultures. The total and particulate PKC ac...Brain neoplasms; Flow cytometry; Glioma; Phorbol ester; Protein kinase C1991
3 Couldwell, William T.Strategies for the management of nonsecreting pituitary adenomasThe two objectives of treating pituitary tumors are: (1) relief of signs and symptoms attributable to mass effect, and (2) correction of hypo - or hypersecretion of adenohypophyseal hormones.7 When nonsecreting tumors are specifically considered, correction of endocrine abnormalities may be of les...Pituitary adenomas; Transsphenoidal surgery1991
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