Honors Theses Open Access
 
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101 Jones, Kathryn K.Hybrid Enzyme-Bimetallic Nanoparticle System for Tandem Oxidation CatalysisMetallic nanoparticles are commonly used as catalysts in industrial and academic settings. Recent observations that bimetallic nanoparticles can have enhanced activity over their monometallic counterparts has increased the interest in their synthesis and application to new catalytic systems. Combini...2020
102 Lan, Yung-ChiHYPO-osmolarity and glucose starvation localizes slm1 to mitochondria- A novel stress response pathwaySynthetic Lethal with Mss4 1 (Slm1) is a key protein found in the crossroad of the Membrane Compartment of Can1 (MCC) and the Membrane Compartment of TORC2 (MCT). The two compartments on the plasma membrane of budding yeast (Saccharomyces cerevisiae) are responsible for APC transporter regulation an...2022
103 Weaver, BradleyHypoxia and the mesenchymal transition in gliomaRecent advances in targeted therapy for cancer have had little influence on survival for patients diagnosed with Glioblastoma (GBM, WHO Grade IV tumors), and median survival time remains stagnant at 12-15 months post diagnosis. Genomic profiling of GBM indicates clear phenotypic subsets of these tum...Glioblastoma multiforme; Gliomas; Hypoxia; Mesenchymal transition2014-04
104 Fackler, Anderson N.Identification of Kin-20 and UNC-119 Knockout suppressors associated with neuronal development and maintenance in C. elegansNeurons comprise the nervous system-the essential signaling and communication system for nearly all multicellular organisms. To coordinate cells across an entire organism, they must grow to be relatively long. Therefore, neurons extend axons from the cell body. Immature neurons extend growth cones a...2018
105 Johnson, KariAnne RencherIdentification of PASK substrates and/or interacting proteinsPAS kinase (PASK) is an evolutionary conserved serine/threonine kinase that appears to have a role in the regulation of cellular energy metabolism. It has previously been shown that mice lacking PASK (PASK"/_ mice) are resistant to the development of hepatic steatosis (lipid accumulation in the live...Biology2012-05
106 Identification of potential causes for increased central line associated bloostream infection rates in the University of Utah NICUThe University of Utah Newborn Intensive Care Unit (UUNICU) has seen a recent increase in rate of Central Line Associated Bloodstream Infection (CLABSI) after an extended period of 965 days with no CLABSI's. Unfortunately, in the last three years, infection rate has been on average 2.6 CLABSI per ye...2023
107 Black, AlyssaIdentifying hybrid male sterility genes in Drosophila PseudoobscuraSpeciation, the process of one species splitting into two separate species, often involves the evolution of hybrid sterility or hybrid inviability. These reproductive isolating barriers are caused by negative interactions between genes called hybrid incompatibilities. Identifying hybrid incompatibil...Infertility, Male -- Genetic aspects Drosophila pseudoobscura -- Genetics Male sterility genes2015-05
108 Ong, ElaineIdentifying Natural Genetic Modifiers of Apoptosis and Retinal DegenerationApoptosis, or cell death, is an integral part of many diseases such as neurodegeneration, retinal degeneration, and cancer, yet it is unclear how apoptosis varies among individuals in a population. Retinitis pigmentosa (RP) is a retinal degeneration disease characterized by phenotypic heterogeneity ...2018
109 Khuu, ScottIdentifying Retinoic Acid Dependent Mechanisms of Neural Crest Epithelial-Mesenchymal TransitionCancer metastasis is one of the distinguishing traits that make the disease difficult to treat. The steps of tumor invasion are similar to a process called epithelial to mesenchymal transition (EMT). Retinoic acid (RA) is shown to inhibit EMT and may cause an increased transcription of the gene, ski...2017
110 Wang, WenyiImaging in a homogeneous aluminum plate by using ultrasonic wavesThis project is about detecting and imaging damage (such as cracks) in a plate by using ultrasonic waves. The waves are generated by a source (an ultrasonic transducer) that is part of a robot that can move on the plate. The waves traveling in the plate are recorded at a receiver (another ultrasonic...Ultrasonic transducer - Mathematics; Kirchoff migration - Research2014-12
111 Au, AlexanderImpact of population density of left atrial remodeling in patients with atrial fibrillationAtrial fibrillation (AF), the most common cardiac arrhythmia and a leading cause of stroke, is characterized by structural changes, or remodeling, in tissues of the left atrium (LA). Late Gadolinium-Enhancement Magnetic Resonance Imaging (LGE-MRI) can noninvasively detect remodeling in the LA, allow...Atrial fibrillation Treatment2012-05
112 Beams, AlexanderImplications of antibiotic use for co-infections when a fitness trade-off for resistance is presentHow much does indiscriminate antibiotic use promote the spread of antibiotic-resistant infections in a population? Assuming a fitness trade-off for resistance exists, it is possible for an antibiotic-vulnerable strain to outlast a resistant type within an untreated host carrying both. That means pru...Drug resistance in microorganisms -- Mathematical models Co-infections2015
113 Owen, Cameron J.Infrared Multiple Photon Dissociation Spectroscopy and Guided Ion Beam Tandem Mass Spectrometry: Experimental and Theoretical investigations of Transition Metal and Lanthandie CationsEmployment of Free Electron Lasers (FELs) and a Guided Ion Beam Tandem Mass Spectrometer (GIBMS) has allowed for the spectroscopic and spectrometric investigations of a variety of ionic complexes, respectively. The data presented in Chapters 2 and 3 of this thesis were obtained using two FELs locate...Netherlands; thermochemical; Natural2019
114 Hansen, MasonInterferon gamma inducible nampt and its role in resisting cancer cell growthThe tumor microenvironment (TME) is very complex and important due to its ability to influence the response of therapies on tumors. Immune cells infiltrate the TME and secrete inflammatory cytokines, such as interferon-gamma (IFNg), which help activate the immune system. This activation leads to an ...2023
115 Tse, JustinThe Linear Algebra of the Last Passage Percolation ModelWe study the linear algebra of the last passage percolation model. In this model, we want to find the statistics of maximal paths through a randomly weighted grid. Specifically we focus on bases of the set of path lengths made from paths. The maximum path length is a deterministic function of a much...2017
116 Allam, JeremyLow-energy satellite transfer from Earth to MarsA new type of satellite transfer that uses half the amount of fuel as conventional transfers has been discovered. This transfer, called a low-energy transfer, proved to work in 1991 when a Japanese satellite successfully went in orbit around the moon using this technique. Since then, more research h...Space vehicles -- Dynamics -- Mathematics Space flight to Mars -- Mathematics2015-04
117 Wallace, Joshua J.Lyman-alpha emission as a probe of galaxy environmentsAs a result of resonant scatterings off hydrogen atoms, Lya emission from star-forming galaxies provides a potential probe of the neutral gas environment around them. In order to determine the utility of Lya emission as a probe of gas environments we study the effects of environmental anisotropy on ...Galaxies - Spectra2014-05
118 Zurbuchen, RudiMacrocyclization of glucagon-like peptide (GLP-1) by thiol-ene reactionMacrocyclization of peptides helps maintain a stable alpha helical structure using a conformational constraining staple. One such peptide, glucagon-like peptide-1 (GLP-1), is a 37 amino acid peptide agonist for the GLP-1 receptor and has the ability to lower blood glucose levels and is responsible ...Peptide hormones - Receptors - Research; Ring formation (Chemistry) - Research; Macrocyndization; GLP-1; Swim kinematics; Pre-pulse inhibition2016-05
119 Pearson, CassidyMajor Urinary Protiens as a signal of genetic Quality and Infection statusThe Hamilton-Zuk hypothesis suggests that susceptibility to infectious disease is so important that many physical traits, particularly secondary sexual characters, will evolve to signal genetic quality for resistance to prospective mates. We expanded upon this theory using the house mouse (Mus muscu...2018
120 Shimko, TylerMapping suppressors of premature sperm activation in C. ElegansThe sperm of the roundworm Caenorhabditis elegans move by a crawling motion, in contrast to mammalian sperm, which exhibit a swimming motion. This method of locomotion makes the sperm of C. elegans an excellent model for examining cell motility. In order to become motile, the sperm must undergo the ...Caenorhabditis elegans -- Spermatozoa; Sperm activation2015-05
121 Tang, AnnaMathematical model of drug resistance in ER+ breast Cancer: the role of the microenvironmentOne of the main obstacles to treating cancer is its ability to evolve and resist treatment. In this project, we are primarily interested mathematically modeling how the cancer microenvironment interacts with cancer cells and affects cancer's response to therapy. We aim to develop the mathematical mo...2023
122 Youatt, Catherine C.Mathematics in Visual Art and BalletCultures all over the globe utilize both mathematics and ballet to understand the world and to express their distinct realities. In this way, mathematics and art interact, both with math creating new visual art fields, like fractal artworks, and with art influencing mathematics, as with Renaissance ...2019
123 Guernsey, MichaelMclr is not solely responsible for pigmentation variation among domestic pigeonsFeather pigmentation in the domesticated rock pigeon, Columba livia, is stunningly diverse. Plumage pigmentation in this, and other, columbid (pigeon and dove) species plays an important role in mate choice and thus is a driving factor in the process of sexual selection. To study the genetic basis o...2012
124 Franchina, Jordan AveryMeasurement of bond dissociation energies of transition metal moleculesMeasuring thermochemical and kinetic properties of chemical systems has always; been a central theme of chemistry. Knowing these properties assists us in assessing; whether or not a chemical reaction is energetically feasible, efficient, and worthwhile.; Theoretical chemistry has now developed suffi...Chemical systems; thermochemical; kinetic; modeling2018-04
125 Green, AustinMeasuring occupancy and occurrence of medium and large mammals in Red Butte Canyon Research Natural Area using motion-activated camera trapsWith expanding urbanization and development, human encroachment on wilderness areas continues to increase. In Utah, much of the once pristine and untouched mountain ecosystems of the Wasatch Front have been developed for recreation and other human use, and this increasing human-wildlife interaction...Red Butte Canyon (Salt Lake County, Utah); Wilderness area monitoring - United States; Wildlife conservation - Utah
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