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| Creator | Title | Description | Subject | Date | ||
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Couldwell, William T.; Jensen, Randy L.; Gillespie, David L. | Celecoxib inhibits meningioma tumor growth in a mouse xenograft model | Background: Treatments for recurrent meningiomas are limited. We previously demonstrated universal expression of COX-2 in meningiomas and dose-dependent growth inhibition in vitro with celecoxib, a COX-2 inhibitor. We therefore tested the effects of celecoxib on meningioma growth in a mouse xenograf... | Meningioma; Cyclooxygenase-2; COX-2; Celecoxib | 2007 |
| 2 |
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Couldwell, William T.; Gillespie, David L.; Jensen, Randy L. | Comparison of the cell lines used in meningoma research | Background: Immortal cell lines and cell lines derived from operative specimens transplanted into animal models are used in meningioma research. We address two criticisms of the mouse xenograft flank tumor model: Why are tumor induction rates derived from operative specimens low and inconsistent? Ar... | CH-157 MN; IOMM-Lee; Meningioma; Xenograft Mouse Model; Flank tumors | 2008 |
| 3 |
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Couldwell, William T.; Apfelbaum, Ronald I. | Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in 105 cases | The traditional boundaries of the transsphenoidal approach may be expanded to include the region from the cribriform plate of the anterior cranial base to the inferior clivus in the anteroposterior plane, and laterally to expose the cavernous cranial nerves and the optic canal. We review our combin... | Transsphenoidal surgery; Chordoma; Craniopharyngioma; Intracranial neoplasm; Meningioma; Pituitary adenoma; Sella turcica; Transsphenoidal craniotomy | 2004 |
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