| | Title | Creator | Description | Subject | Date |
|---|
| 1 |  | Sellar and parasellar metastatic tumors | Couldwell, William T. | The sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures a first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retro... | | 2012-01-01 |
| 2 |  | Senior-Løken syndrome: a syndromic form of retinal dystrophy associated with nephronophthisis | Bernstein, Paul S. | Senior-Løken syndrome (SLS) is an autosomal recessive disease characterized by development of a retinitis (RP)- or Leber congenital amaurosis (LCA)-like retinal dystrophy and a medullary cystic kidney disease, nephronophthisis. Mutations in several genes (called nephrocystins) have been shown to ca... | | 2012-01-01 |
| 3 |  | Shunt insertion in the summer: is it safe? | Kestle, John R. W. | Object. The potential for increased complications related to the arrival of new residents in July each year has not previously been demonstrated in the neurosurgical literature. The authors investigated this phenomenon in children undergoing cerebrospinal fluid shunt surgery. Methods. Data were ob... | Ventriculoperitoneal shunt; July effect; Complication; Shunt insertion | 2006 |
| 4 |  | Significance of bacteriologically positive ventriculoperitoneal shunt components in the absence of other signs of shunt infection | Kestle, John R. W. | The purpose of this study was to determine the significance of "asymptomatic bacteriological shunt contamination" (ABSC), defined as a positive bacteriological culture found on a ventricular shunt component in the absence of bacteria in the cerebrospinal fluid (CSF) culture and/or clinical evidence ... | Ventricular shunt; Shunt infection; Ventriculoperitoneal shunt; Asymptomatic bacteriological; Shunt contamination | 1996 |
| 5 |  | Quality evaluation of controlled clinical information service trials | Mitchell, Joyce A. | Randomized controlled clinical trials are increasingly accepted as tools of computer technology assessment and, therefore, quality evaluation of trials has great theoretical and practical significance. The purpose of this study was to assist the design of evaluation studies and synthesis of publishe... | | 1993-01-01 |
| 6 |  | Quality of life scores compared to objective measures of swallowing function after oropharyngeal chemoradiation | Kendall, Katherine | Objectives: To compare objective measures of swallowing function with patient reports of swallowing-related Quality of Life one year after treatment of oropharyngeal cancer with chemoradiation therapy. Study Design: Patients seen for follow-up at least one year after treatment of oropharyngeal carci... | | 2014-01-01 |
| 7 |  | Radiographic features of tumefactive giant cavernous angiomas | Couldwell, William T. | Giant cavernous angiomas (GCAs) are very rare, and imaging features of GCAs can be very different from those of typical cavernous angiomas (CAs), making them a diagnostic challenge. The purpose of the study was to evaluate the radiographic features of GCAs, with an emphasis on the differentiating fe... | Cavernous angiomas; Cavernous malformations; Tumefactive | 2008 |
| 8 |  | Raman detection of macular carotenoid pigments in intact human retina | Bernstein, Paul S.; Gellermann, Werner | PURPOSE: To develop and test a novel noninvasive optical technique suitable for the objective measurement of macular carotenoid levels in human retina. METHODS: A resonance Raman scattering apparatus was constructed to measure carotenoid levels in flat-mounted human retinas and eyecups and in experi... | Rana pipiens; Spectrum Analysis, Raman; Xanthophylls | 1998 |
| 9 |  | 50 Years of informatics research on decision support: what's next | Mitchell, Joyce A. | Objectives: To reflect on the history, status, and future trends of decision support in health and biomedical informatics. To highlight the new challenges posed by the complexity and diversity of genomic and clinical domains. To examine the emerging paradigms for sup - porting cost-effective, person... | | 2011-01-01 |
| 10 |  | Response to editorial: summer shunting | Kestle, John R. W. | We thank Dr. Scott for his review and comments about our report of shunt surgery complications in the summer. He makes two very good points. Clearly, different databases are suited for different purposes, and the NIS database used in the study by Smith and colleagues is well suited to evaluating t... | | 2006 |
| 11 |  | CT and hemifacial spasm. | Digre, Kathleen B. | Forty-six patients with typical hemifacial spasm had CT. Thirty-eight (83%) were abnormal, including two with surgically documented tumors. Thirty-six had a characteristic dolichoectatic vertebrobasilar artery, with the convexity pointing to the side of the spasm in 92% of the scans. This study sugg... | Hemifacial spasms; Tumors; Dolichoectiatic vertebrobasilar artery | 1988-07 |
| 12 |  | Comment on Aydin, K., et al: Localization of cerebrospinal fliud leaks by gadolinium-enhanced magnetic resonance cisternography: a 5-year single-center experience | Couldwell, William T. | The Author's describe the use of intrathecal Gd-enhanced MR cisternography for the definition of cerebrospinal fluid leaks in 51 patients. They were able to identify the site of leak in 43 of 51 patients (84%). Although the technique is not new, most of the previous articles are found in the neuror... | Cerebrospinal fluid leaks | 2007 |
| 13 |  | Processing of adenovirus 2-induced proteins | Gesteland, Raymond F. | Analysis of (35)S-methionine-labeled extracts of adenovirus 2-infected KB cells revealed 22 virus-induced polypeptide components. Most proteins of the virion were easily detected in extracts of whole cells labeled for short periods between 15 and 30 h after infection; however, several virion compone... | Adenoviridae; Viral Proteins; Protein Precursors; Methionine; Mouth Neoplasms | 1973 |
| 14 |  | Sedimentation field-flow fractionation: a method for studying particulates in cataractous lens | Olson, Randall J.; Coldwell, Karin D.; Compton, Bruce J.; Giddings, John C. | It is shown that the technique of sedimentation field-flow fractionation (sedimentation [sed] FFF) can be used to determine the particle content and particle size distribution of normal and cataractous lenses. A 31-year-old normal human lens, for example, showed a particle content of 1.5% by weight ... | Fractionation; Cataractous Lens; Particulates | 1984 |
| 15 |  | Origin and destiny of adenovirus proteins | Gesteland, Raymond F.; Atkins, John F. | Lytic infection of human cells by adenovirus proceeds by a temporal expression of genes. Classically two phases have been defined: an early phase, which includes events occurring before the onset of DNA synthesis (8 hours), and a late phase, including events whose existence depends on the onset of... | Protein Biosynthesis; DNA, Viral; Adenoviridae; RNA, Viral; Time Factors | 1975 |
| 16 |  | Silicon-based, three-dimensional neural interface: manufacturing processes for an intracortical electrode array | Normann, Richard A.; Campbell, Patrick K.; Jones, Kelly E.; Huber, Robert J.; Horch, Kenneth W. | A method has been developed for the manufacture of a "three-dimensional" electrode array geometry for chronic intracortical stimulation. This silicon based array consists of a 4.2 x 4.2 x 0.12 mm thick monocrystalline substrate, from which project 100 conductive, silicon needles sharpened to facilit... | Electric Stimulation; Electrodes, Implanted; Sensory Cortex; Intracortical Electrode Array | 1991 |
| 17 |  | Simian virus 40-specific polypeptides in Ad2+ND4- infected cells | Gesteland, Raymond F. | A comparison of the proteins synthesized in human cells at late times after infection with adenovirus (Ad2) and with the adeno-simian virus 40 (SV40) hybrid viruses revealed polypeptides of 30,000 and 92,000 molecular weight specific for the hybrid viruses Ad2+ND1 and Ad2+ND4, respectively. Cell-fre... | Molecular Weight; Peptide Biosynthesis; RNA, Messenger; Viral Proteins | 1976 |
| 18 |  | Robust estimation of fetal heart rate variability using Doppler ultrasound. | Varner, Michael W.; Clark, Edward B.; Fernando, Kumari L.; Mathews, V. John | This paper presents a new measure of heart rate variability (HRV) that can be estimated using Doppler ultrasound techniques and is robust to variations in the angle of incidence of the ultrasound beam and the measurement noise. This measure employs the multiple signal characterization (MUSIC) algori... | Prenatal Ultrasonography; Fetal Heart Rate; Blood Flow Velocity; Algorithms | 2003-08 |
| 19 |  | 100 electrode intracortical array: structural variability | Normann, Richard A.; Campbell, Patrick K.; Jones, Kelly E. | A technique has been developed for fabricating three dimensional "hair brush" electrode arrays from monocrystalline silicon blocks. Arrays consist of a square pattern of 100 penetrating electrodes, with 400 microns interelectrode spacing. Each electrode is 1.5mm in length and tapers from about 100 m... | Microelectrode arrays; Stimulation; Micromachining | 1990 |
| 20 |  | Mobility performance with a pixelized vision system | Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
| 21 |  | Signal integration at the pedicle of turtle cone photoreceptors: an anatomical and electrophysiological study | Normann, Richard A.; Kolb, Helga; Lasater, Eric M. | The morphology of the axon which connects the cell body and pedicle of turtle cone photoreceptors was studied by light and electron microscopy. The axon which contains numerous synaptic vesicles, some endoplasmic reticulum, and a few cisternae is basically filled with cytoplasm. The length of the ax... | Cone Photoreceptor, Voltage Clamp; Isolated Cells; Input Resistance; Cell Body-Pedicle Coupling | 1989 |
| 22 |  | Functional reorganization of primary visual cortex induced by electrical stimulation in the cat. | Normann, Richard A. | Compared to the high degree of plasticity observed in a juvenile, mature sensory cortices have long been held to be immutable but, recently, researchers have suggested some plasticity persists in the mature cortex. Cortical reorganization has particular saliency to the development of a cortically ba... | Cat; Electrophysiology; Phosphene; Plasticity; Receptive Field; Striate Cortex | 2005 |
| 23 |  | Encoding mechanisms for sensory neurons studied with a multielectrode array in the cat dorsal root ganglion | Normann, Richard A.; Shoham, Shy | Recent advances in microelectrode array technology now permit a direct examination of the way populations of sensory neurons encode information about a limb's position in space. To address this issue, we recorded nerve impulses from about 100 single units simultaneously in the L6 and L7 dorsal root ... | Sensory; Encoding; Multielectrode; Dorsal Root Ganglion; Cutaneour; Muscle | 2004 |
| 24 |  | Three-dimensional architecture for a parallel processing photosensing array | Normann, Richard A.; Johansson,Torbjorn; Abbasi, Masoud; Huber, Robert J. | A three-dimensional architecture for a photosensing array has been developed. This silicon based architecture consists of a 10 x 10 array of photosensors with 80 microns diameter, through chip interconnects to the back side of a 500 microns thick silicon wafer. Each photosensor consists of a 300 x 3... | Retina; Optics; Silicon; Photosensing | 1992 |
| 25 |  | Silicon carbide enhanced thermomigration | Normann, Richard A.; Abbasi, Masoud; Johansson,Torbjorn | The widespread acceptance of thermomigration technology to produce through-chip interconnects has been impaired by (i) a random walk of the Si-Al liquid eutectic inclusion as it traverses the wafer, and (ii) a ?surface barrier? which allows thermomigration of only relatively large inclusions. In ... | Silicon Dioxide; Thermometers; Transducers; Thermomigration Technology; Infrared Lamps | 1992 |
