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1 Kestle, John R. W.Potentially useful outcome measures for clinical research in pediatric neurosurgeryThe choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed more sophisticated measures of the effect of an intervention. M...Pediatric neurosurgery2005
2 Schmidt, Meic H.Lumbosacral ependymomas: a review of the management of intradural and extradural tumorsObject. The goal of this study was to review the management of intra- and extradural ependymomas. Spinal ependymomas most commonly occur as intramedullary tumors throughout the spinal axis. In the lumbosacral region, ependymomas are most commonly associated with the conus medullaris and cauda equina...Intradural ependymoma; Extradural ependymoma; Lumbosacral lesion2003
3 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 3: assessment of economic outcomeStandards. There is insufficient evidence to recommend a standard for assessment of economic outcome following lumbar fusion for degenerative disease. Guidelines. There is insufficient evidence to recommend a guideline for assessment of economic outcome following lumbar fusion for degenerative dis...Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Treatment outcome; Economic outcome2005
4 Kestle, John R. W.Multicenter prospective cohort study of the Strata valve for the management of hydrocephalus in pediatric patientsObject. Previous reports suggest that adjustable valves may improve the survival of cerebrospinal fluid shunts or relieve shunt-related symptoms. To evaluate these claims, the authors conducted a prospective multicenter cohort study of children who underwent placement of Strata valves. Methods. Pat...Ventriculoperitoneal shunt; Strata valve; Adjustable valves; Pediatric neurosurgery2005
5 Couldwell, William T.Porous polyethylene implant for cranioplasty and skull base reconstructionObject. Cranial reconstruction after skull base surgery is important for restoration of function and cosmesis. The authors describe their experience with the Medpor porous polyethylene implant for cosmetic cranioplasty and reconstruction after skull base surgery. Methods. Medpor, a biocompatible i...2004
6 Couldwell, William T.Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging findingObject. The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their signifi...2005
7 Couldwell, William T.Transsphenoidal microsurgical treatment of Cushing disease: postoperative assessment of surgical efficacy by application of an overnight low-dose dexamethasone suppression testObject. Transsphenoidal adenomectomy with resection of a defined pituitary adenoma has been the treatment of choice for CD for the last 30 years. Surgical resection, however, may not always result in long-term remission of CD. This is particularly important in light of the high risk of morbidity and...2003-01-01
8 Couldwell, William T.Predictive value of serum prolactin levels measured immediately after transsphenoidal surgeryObject. Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and...Prolactin; Transsphenoidal surgery; Pituitary adenoma; Prolactinoma; Transsphenoidal approach2002
9 Garber, SarahNeurosurgical complications of direct thrombin inhibitors - catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatranDabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. Large randomized clinical trials have shown higher doses of dabigatran (150 mg taken twice daily) to be superior to warfarin in terms of stroke and systemic embolism rates in patients with nonvalvula...2012-01-01
10 Couldwell, William T.Response to Craniopharyngioma adherence to the hypothalamusTo The Editor: We have viewed with great interest the special supplement published by Neurosurgical Focus in January 2013 (Neurosurgical Focus, Video Atlas of Operative Surgery: Intraventricular Lesions: Microscopic and Endoscopic Approaches, Vol 34: January 2013) in which a compilation of videos de...2014-01-01
11 Couldwell, William T.Sellar and parasellar metastatic tumorsThe sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures a first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retro...2012-01-01
12 Jensen, Randy LynnTreatment-related brain tumor imaging changes: so-called "pseudoprogression" vs. tumor progression: Review and future research opportunitiesBackground: Glioblastoma multiforme (GBM) has a dismal prognosis despite aggressive therapy. Initial diagnosis and measurement of response to treatment is usually determined by measurement of gadolinium-enhanced tumor volume with magnetic resonance imaging (MRI). Unfortunately, many GBM treatment mo...2013-01-01
13 Couldwell, William T.Transnasal excerebration surgery in ancient Egypt: Historical vignetteAncient Egyptians were pioneers in many fields, including medicine and surgery. Our modern knowledge of anatomy, pathology, and surgical techniques stems from discoveries and observations made by Egyptian physicians and embalmers. In the realm of neurosurgery, ancient Egyptians were the first to elu...2012-01-01
14 Couldwell, William T.Transtemporal approach to the removal of a lateral pontine tumorThis video demonstrates a very useful trajectory to a pontine lesion. A 68-year-old man presented with tongue numbness and weakness. The approach used was a transtemporal presigmoid retrolabyrinthine approach to enable an orthogonal trajectory to the lateral pons. Following the transtemporal opening...2014-01-01
15 Couldwell, William T.Intracranial hypotension as a complication of lumbar puncture prior to elective aneurysm clippingBackground: Lumbar dural defects are an uncommon but important cause of persistent intracranial hypotension in the neurosurgical population. We present a case of intracranial hypotension after elective craniotomy due to a lumbar puncture performed 3 weeks earlier. Case Description: A 55‑year‑old...2014-01-01
16 Couldwell, William T.Intracranial hypotension in the setting of concurrent perineural cyst rupture and subarachnoid hemorrhageAlthough most patients with intracranial hypotension typically present with headaches, the rest of the clinical spectrum is characteristically non-specific and often quite variable. In a patient with concurrent pathologies that can produce a similar clinical picture, a high index of suspicion must b...2013-01-01
17 Couldwell, William T.Intraoperative aneurysmal subarachnoid hemorrhage after rupture of a previously undiagnosed intracranial aneurysm during Chiari decompression: case report and literature reviewType 1 Chiari malformation occurs when caudal displacement of cerebellar tonsils below the level of foramen magnum obstructs the normal flow of cerebrospinal fluid (CSF) between the cranial and spinal spaces, a condition that often needs surgical decompression to restore normal CSF circulation. Abru...2014-01-01
18 Couldwell, William T.Management of meningiomas involving the transverse or sigmoid sinusMeningiomas that invade the transverse or sigmoid sinuses are uncommon tumors that are challenging to treat surgically. Although the risk of recurrence is associated with the extent of resection, complete removal of meningiomas in these locations must be balanced with avoidance of venous outflow obs...2013-01-01
19 Couldwell, William T.Efficacy of clip-wrapping in treatment of complex pediatric aneurysmsPurpose: Pediatric aneurysms (PAs) are distinct from their adult counterparts with respect to typical location, aneurysm type, and known predisposing risk factors. Many strategies have been employed to treat PAs, but, although it has been used frequently in adults, clip-wrapping in pediatric patient...2012-01-01
20 Couldwell, William T.Giant pituitary tumor combined approachNishioka et al. have provided a review of 29 patients with large pituitary adenomas who underwent surgery through a simultaneous transsphenoidal and transcranial approach at their institution during a 7-year period. Large adenomas with hourglass constriction, complex lobulations, and asymmetric exte...2012-01-01
21 Dailey, Andrew T.Lateral mass screw fixation in the cervical spineTo The Editor: We read with interest the article by Kawabata et al.15 (Kawabata S, Watanabe K, Hosogane N, et al: Surgical correction of severe cervical kyphosis in patients with neurofibromatosis Type 1. Report of 3 cases. J Neurosurg Spine 18:274-279, March 2013). Reconstructive spinal surgery has...2014-01-01
22 Patel, Bhupendra C.Lateral orbital wall approach to the cavernous sinus: laboratory investigationObject. Lesions of the cavernous sinus remain a technical challenge. The most common surgical approaches involve some variation of the standard frontotemporal craniotomy. Here, the authors describe a surgical approach to access the cavernous sinus that involves the removal of the lateral orbital wal...2012-01-01
23 Schmidt, Meic H.Isolated intramedullary neurosarcoidosis of the thoracic spine: case report and review of the literatureSarcoidosis can involve the central nervous system in approximately 5-15% of cases. Any part of the nervous system can be involved, so presentation can be quite varied. Isolated disease of the spinal cord is even less common and reports are limited to single cases and small series. Although in the s...2012-01-01
24 Schmidt, Meic H.Is vertebral augmentation the right choice for cancer patients with painful vertebral compression fractures?Cancer-related fractures of the spine are different from osteoporotic ones, not only in pathogenesis but also in natural history and treatment. Higher class evidence now supports offering balloon kyphoplasty to a patient with cancer, provided that the pain is significant in intensity, has a position...2012-01-01
25 Garber, SarahSpinal arteriovenous fistulas in children with hereditary hemorrhagic telangiectasia: report of 2 casesHereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant angiodysplasia with high penetrance and variable expression. The manifestations of HHT are often age related, and spinal arteriovenous fistula (AVF) may be the initial presentation of HHT in young children. Because spinal AVFs are...2012-01-01
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