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Creator | Title | Description | Subject | Date |
| 1 |
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Lam, LeAnn | Pre-clinical animal model for ovarian cancer using live imaging system | Development of a live imaging animal model for orthotopic ovarian cancers in order to better understand disease mechanisms and response to potential anticancer drug treatments. | Ovarian cancer; Cancer; Animal model; Live imaging; Cell culture; ACCESS | 2015-04-14 |
| 2 |
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Macleod, Robert S. | Sensitivity and specificity of substrate mapping: An in silico framework for the evaluation of electroanatomical substrate mapping strategies | Background - Voltage mapping is an important tool for characterizing proarrhythmic electrophysiological substrate, yet it is subject to geometric factors that influence bipolar amplitudes and thus compromise performance. The aim of this study was to characterize the impact of catheter orientation on... | | 2014-01-01 |
| 3 |
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Vardhan, Avantika | Characterizing growth patterns in longitudinal MRI using image contrast | Understanding the growth patterns of the early brain is crucial to the study of neuro-development. In the early stages of brain growth, a rapid sequence of biophysical and chemical processes take place. A crucial component of these processes, known as myelination, consists of the formation of a myel... | | 2014-01-01 |
| 4 |
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Gerig, Guido | Neuro imaging research lab | | | 2012 |
| 5 |
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Christensen, Douglas A. | Ultrasound beam simulations in inhomogeneous tissue geometries using the hybrid angular spectrum method | The angular spectrum method is a fast, accurate and computationally efficient method for modeling wave propagation. However, the traditional angular spectrum method assumes that the region of propagation has homogenous properties. In this paper, the angular spectrum method is extended to calculate u... | | 2012-01-01 |
| 6 |
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Jenson, Justin Michael; Bock, Susan C. | Mitigating spinal cord injury | How would your life change if you became one of the 15,000 Americans to suffer a spinal cord injury this year? Trauma to the spinal cord causes immediate loss of function below the level of the injury. Then, in the hours and days after the accident, the body's secondary injury response may extend ... | Trapeze Interactive Poster | 2010-03-15 |
| 7 |
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Collins, Zachary J.; Poelzing, Steven | Characterization of a four-camera ratiometric optical mapping system | Electrical activity precedes calcium mediated heart contractions. Optical mapping takes advantage of minimally invasive fluorescent molecular probes to image both electrical and calcium activity. These molecular probes allow for ratiometric imaging. We characterize a four camera system capable of... | Optical mapping; Ratiometric imaging; Di-4-ANEPPS; Indo-1; Trapeze Interactive Poster | 2010-03-15 |
| 8 |
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Normann, Richard A. | Oscillations in rod and horizontal cell membrane potential: evidence for feed-back to rods in the vertebrate retina | 1. Rods and horizontal cells were studied with intracellular recordings in the retina of the toad, Bufo marinus; 161 cells were from the eyecup preparation and thirty were from the isolated perfused retina. 2. Of these cells, 39% exhibited either transient or sustained oscillations of membrane poten... | Retina; Photoreceptors; Toads; Adaptation, Ocular | 1976 |
| 9 |
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Gesteland, Raymond F. | Processing of adenovirus 2-induced proteins | Analysis of (35)S-methionine-labeled extracts of adenovirus 2-infected KB cells revealed 22 virus-induced polypeptide components. Most proteins of the virion were easily detected in extracts of whole cells labeled for short periods between 15 and 30 h after infection; however, several virion compone... | Adenoviridae; Viral Proteins; Protein Precursors; Methionine; Mouth Neoplasms | 1973 |
| 10 |
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Horch, Kenneth W.; Lawrence, Steve M.; Dhillon, Gurpreet S. | Acute peripheral nerve recording characteristics of polymer-based longitudinal intrafascicular electrodes | We examined the recording characteristics of two different types of polymer-based longitudinal intrafascicular electrodes (LIFEs) in peripheral nerve: single-stranded (s-polyLIFEs) and multistranded (m-polyLIFEs). Recordings were also made from Pt-Ir wire-based electrodes (PtIrLIFEs) as a control. T... | Sciatic Nerve; Intrafascicular Electrodes, Peripheral Nerve Recording | 2004 |
| 11 |
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Christensen, Douglas A. | Acoustic droplet vaporization, cavitation, and therapeutic properties of copolymer-stabilized perfluorocarbon nanoemulsions | Acoustic and therapeutic properties of Doxorubicin (DOX) and paclitaxel (PTX)-loaded perfluorocarbon nanoemulsions have been investigated in a mouse model of ovarian cancer. The nanoemulsions were stabilized by two biodegradable amphiphilic block copolymers that differed in the structure of the hydr... | Cancer therapy; Targeted drug delivery; Nanobubbles; Ultrasound; Perfluoropentane | 2009 |
| 12 |
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Christensen, Douglas A. | Ultrasound beam propagation using the hybrid angular spectrum method | We introduce a fast and accurate numerical method for simulating the propagation of an ultrasound beam inside inhomogeneous tissue for mapping beam absorption, refraction and diffraction in the body. The technique, called the hybrid angular spectrum method, is an extension of the angular spectrum m... | Ultrasound beam propagation; Medical ultrasound; Inhomogeneous tissue; Beam simulation | 2008-08 |
| 13 |
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Normann, Richard A. | Control of retinal sensitivity. I. Light and dark adaptation of vertebrate rods and cones | Rods and cones in Necturus respond with graded hyperpolarization to test flashes spanning about 3.5 log units of intensity. Steady background levels hyperpolarize the rods, and the rod responses become progressively smaller as background level is increased. In cones, higher background levels reduce... | Retina;Light and Dark Adaptation; Recepters; Bipolars; Ganglion Cells | 1974 |
| 14 |
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Horch, Kenneth W. | Intraspinal microstimulation using cylindrical multielectrodes | A cylindrical multielectrode system specifically designed for intraspinal microstimulation was mechanically and electrically evaluated in the ventral horn of the feline lumbo-sacral spinal cord. Electrode insertions proved to be straight as evaluated from radiographs. Impedances were measured in s... | Cylindrical multielectrode; Microstimulation; Neural prosthesis; Current distance constants; Electrode array; Spinal cord stimulation | 2006-02 |
| 15 |
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Christensen, Douglas A.; Furse, Cynthia M. | Problem and treatment of DC offsets in FDTD simulations | This paper discusses the causes of and some solutions to the commonly observed problem of dc field offsets in finite-difference time-domain (FDTD) simulations. DC electric and magnetic field offsets are shown to be valid calculated responses of the modeled systems, resulting from interaction betwee... | Finite-difference time-domain method; Direct current offsets; Waveforms | 2000-08 |
| 16 |
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Normann, Richard A.; Chandler, John P. | Effects of calcium ions on L-type horizontal cells in the isolated turtle retina | A technique by which the retina can be isolated from the turtle eye is described. Scanning electron microscopy revealed morphological variability between preparations and also between regions of the same one. Large areas were often totally free of any pigment epithelial cells, yet contained a high p... | Retina; Calcium; Horizontal Cell; Turtle | 1990 |
| 17 |
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Normann, Richard A. | Signal transmission from red cones to horizontal cells in the turtle retina | 1. Intracellular recordings were made from L-type horizontal cells in the retina of the turtle Pseudemys scripta elegans. The responses were evoked by 500 msec pulses of 'white' light. 2. L-type horizontal cells were classified as either, 'small receptive field' s.r.f. or 'large receptive field' l.r... | Turtles; Synapses; Retina; Photoreceptors | 1979 |
| 18 |
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Horch, Kenneth W. | Muscle recruitment through electrical stimulation of the lumbo-sacral spinal cord | The goal of this study was to determine the feasibility of producing graded muscle contraction in individual muscles or muscle groups by electrically stimulating motor neurons in the lumbo-sacral spinal cord. Recruitment curves were obtained for quadriceps, tibialis anterior and triceps surae/pl... | Functional neuromuscular stimulation (FNS); Motor pools, Muscle recruitment, Spinal cord stimulation | 2000 |
| 19 |
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Gesteland, Raymond F.; Weiss, Robert B. | Efficient shine- Dalgarno sequence but not translation is necessary for LacZ mRNA stability in Escherichia coli | The 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation c... | Protein Biosynthesis; Ribosomes; Escherichia coli; Shine-Dalgarno Sequence | 1994 |
| 20 |
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Horch, Kenneth W. | Classification of action potentials in multi unit intrafascicular recordings using neural network pattern recognition techniques | Neural network pattern-recognition techniques were applied to the problem of identifying the sources of action potentials in multi-unit neural recordings made from intrafascicular electrodes implanted in cats. The network was a three-layer connectionist machine that used digitized action potenti... | Intrafascicular electrodes; Multi-unit neural activity; Artificial neural networks | 1994 |
| 21 |
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Horch, Kenneth W.; Christensen, Douglas A. | Accelerated 4-year bachelors/masters degree program in biomedical engineering | In response to the need for providing advanced engineering education in a shorter time period than is currently possible by traditional curricula, we have created an Accelerated Dual Degree program in biomedical engineering. The purpose of this pilot program is to attract the brightest students, g... | Accelerated dual-degree program | 2002 |
| 22 |
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Horch, Kenneth W. | Closed loop control of ankle position using muscle afferent feedback with functional neuromuscular stimulation | This paper describes a closed-loop functional neuromuscular stimulation system that uses afferent neural activity from muscle spindle fibers as feedback for controlling position of the ankle joint. Ankle extension against a load was effected by neural stimulation through a dual channel intrafasc... | Neuromuscular stimulation; Functional neuromuscular stimulation (FNS); Neural electrodes | 1996 |
| 23 |
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Christensen, Douglas A. | Resonant inductive applicator for neck hyperthermia | We have designed and phantom tested an inductive applicator especially suited for producing hyperthermia in cancerous regions in the neck. The applicator is tuned to resonate near 27 MHz; its inductive nature has the advantage of efficient coupling to the irregular neck anatomy. An inhomogeneou... | Hyperthermia applicator; Phantom tests | 1989 |
| 24 |
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Hansen, Mark S.; Healy, Lindsey J.; Johnson, Christopher R.; Capecchi, Mario R.; Keller, Charles; Jones, Greg M. | Virtual histology of transgenic mouse embryos for high-throughput phenotyping. | A bold new effort to disrupt every gene in the mouse genome necessitates systematic, interdisciplinary approaches to analyzing patterning defects in the mouse embryo. We present a novel, rapid, and inexpensive method for obtaining high-resolution virtual histology for phenotypic assessment of mouse ... | Forkhead Transcription Factors; Paired Box Transcription Factors | 2006 |
| 25 |
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Gesteland, Raymond F.; Atkins, John F.; Felden, Brice; McCutcheon, John P. | Probing the structure of the Escherichia coli 10Sa RNA (tmRNA) | The conformation of the Escherichia coli 10Sa RNA (tmRNA) in solution was investigated using chemical and enzymatic probes. Single- and double-stranded domains were identified by hydrolysis of tmRNA in imidazole buffer and by lead(II)-induced cleavages. Ribonucleases T1 and S1 were used to map unpai... | Covariation; Pseudoknot; Structural Probing; 10Sa RNA; tmRNA | 1997 |
