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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Hobbs, Maurine R.; Granger, Donald Lee | Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population | Polymorphisms in the inducible nitric oxide synthase gene (NOS2) promoter have been associated with clinical outcome from malaria. These include a CCTTT repeat (CCTTTn) 2.5 kilobases upstream from the NOS2 transcription start site, and two single nucleotide substitutions: G-->C at position -954 (G-9... | Papua New Guinea; Oceanic Ancestry Group; Repetitive Sequences, Nucleic Acid | 2003 |
| 2 |
 | Coley, Phyllis D.; Kursar, Thomas A. | Novel DNA-based microfluorimetric method to evaluate antimalarial drug activity | This paper describes the development of a novel microfluorimetric assay to measure the inhibition of Plasmodium falciparum based on the detection of parasitic DNA by intercalation with PicoGreen®. The method was used to determine parasite inhibition profiles and 50% inhibitory concentration values ... | Microfluorimetric assay; Plasmodium falciparum; Chloroquine; Drug discovery | 2004 |
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