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CreatorTitleDescriptionSubjectDate
1 Gesteland, Raymond F.; Ives, Jeffrey T.; Stockham, Thomas G.Automated film reader for DNA sequencing based on homomorphic deconvolutionAn automated reader for electrophoresis based DNA sequencing methods is described that provides fast and accurate sequence determination. Digitized sequencing lanes are processed with homomorphic blind deconvolution in preparation for peak detection, interlane alignment, peak refinement and base cal...Sequence Analysis; Electrophoresis; Automated Film Reader; Homomorphic Deconvolution1994
2 Beckerle, Mary C.Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeletonLIM domains are present in a number of proteins including transcription factors, a protooncogene product, and the adhesion plaque protein zyxin. The LIM domain exhibits a characteristic arrangement of cysteine and histidine residues and represents a novel zinc binding sequence (Michelsen et al., ...Zyxin; Cysteine-rich proteins; cCRP; Actin; LIM domains1994
3 Olivera, Baldomero M.Conodipine-M, a novel phospholipase A2 isolated from the venom of the marine snail Conus magusWe describe the purification and first biochemical characterization of an enzymatic activity in venom from the marine snail Conus magus. This enzyme, named conodipine-M, is a novel phospholipase A2 with a molecular mass of 13.6 ĸDa and is comprised of two polypeptide chains linked by one or more di...Conotoxins; Conodipine-M; Conus magus1994
4 Adler, Frederick R.Construction of multidimensional clustered patternsEcological processes often depend upon the patterning, as well as the absolute density, of resources. In this paper, we develop methods for describing pattern from the perspective of the organism encountering and exploiting the resources, and for reconstructing pattern from the description.Algorithms; clustered resources; foraging1994
5 Bohs, Lynn A.Cyphomandra (Solanaceae)Unusual ecological aspects of Cyphomandra include its pollination syndrome and herbivore relationships. Male euglossine bees may be important pollinators of Cyphomandra flowers, and the primary attractants may not be pollen, but odor substances secreted by the anther connectives. Specialized herbi...Cyphomandra; Latin America1994
6 Adler, Frederick R.Defended fortresses or moving targets? Another model of inducible defenses inspired by military metaphorsWe use a common framework to compare three models of plant strategies to confront herbivory: constitutive defense, optimal inducible defense, and the "moving target." Plants with constitutive defenses retain a fixed defensive phenotype. Plants with optimal inducible defenses respond to attack by inc...Constitutive defense; optimal inducible defense; phenotype1994
7 Gesteland, Raymond F.; Weiss, Robert B.Efficient shine- Dalgarno sequence but not translation is necessary for LacZ mRNA stability in Escherichia coliThe 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation c...Protein Biosynthesis; Ribosomes; Escherichia coli; Shine-Dalgarno Sequence1994
8 Adler, Frederick R.General test for interaction modificationHow can measurements of population dynamics be used to deduce the mechanisms of interaction in an assemblage of species? We present a technique to use such measurements to distinguish among assemblages of species with no direct interactions, sets of species influenced predominantly by pairwise inter...Species; Population; Dynamics1994
9 Beckerle, Mary C.; Davis, Darrell R.; Winge, Dennis R.Mutational analysis of the metal sites in an LIM domainSite-directed mutagenesis was carried out map the residues that form the two Zn(I1) sites within a LIM domain. The C-terminal LIM domain derived from the cysteine-rich protein was utilized for this analysis and is referred to as LIMB.LIM domains; Metal-binding1994
10 Bohs, Lynn A.New species of Solanum section Cyphomandropsis (Solanaceae) from BoliviaA new species of Solanum sect. Cyphomandropsis (Solanaceae), S. hibernum, is described from the western part of Dept. Santa Cruz, Bolivia. Its strongly discolorous leaves densely covered below with white dendritic hairs distinguish it from the other species in the section.Solanum hibernum; Cyphomandropsis1994
11 Olivera, Baldomero M.Nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImIWe report the isolation, characterization, and total synthesis of a small peptide ligand for nicotinic acetylcholine receptors (nAChRs). It is highly active against the neuromuscular receptor in frog but noitn mice. In contrast, it induces seizures when injected centrally in mice and rats, suggesti...Conotoxins; a-conotoxin ImI1994
12 Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M.rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshiftBase pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ...Frameshifting; Escherichia coli; Binding Sites; Base Composition1994
13 Seger, JonSexual dimorphism in the HymenopteraSpectacular sex differences of many kinds occur abundantly among the wasps, bees and ants that make up the insect order Hymenoptera. In some cases these differences are so extreme that males and females of the same species have been classified in different genera for decades, until a chance observa...Reproductive; Insect; Morphology1994
14 Gesteland, Raymond F.; Atkins, John F.; Tuohy, Therese M.Uninterrupted translation through putative 12-nucleotide coding gap in sequence of carA: business as usualPrevious work of others reported an untranslated stretch of 12 nucleotides in the 5' coding sequence of carA from Pseudomonas aeruginosa. However, N-terminal protein sequencing of carA-lacZ translational fusions shows that these 12 nucleotides are normally translated in a continuous triplet manner, ...Base Sequence; Protein Biosynthesis; Sequence Deletion1994
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