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TitleCreatorDescriptionSubject
851 Systemic Disorders With Optic Nerve and Retinal FindingsAAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietyA 42-year old woman presented with a history of severe brow pain and 4 days of progressive visual loss OD. There was no increased pain on ocular rotation. Aside from heavy menses, she denied any significant past medical history. Her examination revealed acuity NLP OD, 20/25 OS; color vision 9/10 OS;...Syphilis
852 Lid Lag (PPT)Shirley H. Wray, MD, PhD, FRCPThe classical eye signs of thyroid associated ophthalmopathy (TAO) of Graves' Disease is illustrated by case ID925-4. This 50 year old woman with TAO is included in the collection because she illustrates very well lid lag (persistent elevation of the upper eyelid in downgaze) - von Graefe sign Eyeli...Lid Lag; Bilateral Exophthalmos; Restrictive Orbitopathy of Graves' Disease
853 Visual NeglectShirley H. Wray, MD, PhD, FRCPThe patient following infarction of the non-dominant right parietal lobe has visual hemi-neglect on the left. Review: (ref 2) Patient's with hemi-neglect ignore or fail to attend to stimuli on the side of space contralateral to their lesion. Neglect can be multimodal in that all stimuli whether audi...Impaired Initiation of Horizontal Saccades to the Left; Deviation of the Eyes to the Left Under Closed Eyelids; Normal Pursuit Eye Movements; Parietal Lobe Infarct; Visual Neglect
854 Thyroid Associated Orbitopathy (TAO) (PPT)Shirley H. Wray, MD, PhD, FRCPThis 71 year old woman (Wray case 925-4) was referred with bilateral optic neuropathy and thyroid associated ophthalmopathy (TAO) of Graves' Disease. She had been treated for primary hyperthyroidism on three occasions with radioactive iodine and was taking Tapazole 5 mg daily. Neuro-ophthalmological...Bilateral Lid Retraction; Lid Lag; Bilateral Exophthalmus; Restrictive Orbitopathy of Graves' Disease; Lid Retraction; Thyroid Orbitopathy; Restriction Syndromes; Thyroid Eye Disease; Thyroid-Associated Ophthalmopathy; Blow-Out Fracture
855 Familial Amyotrophic Lateral SclerosisShirley H. Wray, MD, PhD, FRCPThis 58 year old woman was referred to Dr. Robert Brown in March 1995 for evaluation of slurred speech. She remained under his care until her death. On examination she had signs of a pseudobulbar palsy: Dysarthria and dysphagia Diminished palatal movement with positive gag bilaterally Diminished rap...Supranuclear Paralysis of Up and Downgaze Degeneration; Convergence Insufficiency; Slow Hypometric Horizontal Saccades;; Saccadic Breakdown of Horizontal Pursuit; Bulbar Palsy; Familial Amyotrophic Lateral Sclerosis; Lou Gehrig's Disease; CNS -Degeneration; Superoxide Dismutase (SOD1) Gene
856 Chest CT: ThymomaRobert A. Novelline, MDSlideshow describing condition.External Ophthalmoplegia; Generalized Myasthenia Gravis; Myasthenic Lid Twitch; Ocular Myasthenia Gravis; Tensilon Test; Thymolipoma; Unilateral Lid Retraction; Unilateral Myasthenia Gravis; Unilateral Ptosis
857 Paraneoplastic Disease (PowerPoint)AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietyThis 46-year-old woman noted progressive bilateral visual loss over a 10-month period. She had a malignant melanoma removed from her right thigh 2 years ago and excisional biopsy of an inguinal node metastasis 8 months ago. She also complained of poor night vision and rare intermittent ""sparkles"" ...Paraneoplastic Disease
858 Radiation Retinopathies (PowerPoint)AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietyRadiation retinopathy may mimic diabetic or hypertensive optic neuropathy. A history of irradiation to the eye, orbit, or head is mandatory. Radiation retinopathy usually occurs many months after radiation therapy.Radiation Retinopathy
859 Brain Control of Horizontal Saccadic Eye MovementsShirley H. Wray, MD, PhD, FRCPPowerPoint lecture describing brain control of horizontal saccadic eye movements.Acquired Ocular Motor Apraxia; Alzheimer's Disease with Mild Extrayramidal Signs; Cerebral Cortex; CNS Degeneration; Complete Paralysis of Voluntary Horizontal Saccades on Command to Look Left; Facial Tremor; Frontotemporal Dementia; Impaired Pursuit; Inability to Make a Refixation Saccade on Comma...
860 Papilledema and Resolution (PowerPoint)AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietyThis 42-year-old male with pseudotumor cerebri and chronic papilledema demonstrated refractile bodies, which can be seen with chronic optic disc edema. This image shows the chronic papilledema at presentation, with associated refractile hyaline bodies at the disc periphery in both eyes.Pseudotumor Cerebri/Papilledema; Edema; Papilledema and Resolution
861 Bilateral PtosisShirley H. Wray, MD, PhD, FRCPA PowerPoint slideshow of diagnosed patients.Bilateral Ptosis; Facial Weakness; Full Eye Movements; MuSK Antibody Myasthenia Gravis; Tongue Atrophy; Myasthenia Gravis
862 Ocular Motor ApraxiaShirley H. Wray, MD, PhD, FRCPPresentation covering an overview of Ocular Motor Apraxia. See also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/255, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/253, and http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/252Congenital Ocular Motor Apraxia; Head Thrust; Ocular Motor Apraxia
863 Alexia Without AgraphiaShirley H. Wray, MD, PhD, FRCPThe patient is a 69 year old left handed man with a history of hypertension, insulin dependent diabetes mellitus and atrial fibrillation. Treated with coumadin, adjusted to keep the INR between 2 and 3. On the morning of admission he awoke at 4 a.m., sat momentarily on the side of the bed and then s...Pure Alexia; Color Anomia; Right Homonymous Hemianopia; Alexia Without Agraphia; Infarct of the Left Visual Cortex and Splenium of the Corpus Callosum; Disconnection Syndrome; Occipital Infarct
864 Constructional ApraxiaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Apraxia of the Left Hand; Constructional Apraxia; Degenerative CNS Disease; Dressing Apraxia; Progressive Lobar Atrophy; Right Parietal Lobe
865 Charles Bonnet SyndromeShirley H. Wray, MD, PhD, FRCPThe patient is a 79 year old woman with a chief complaint of visual hallucinations. She carries a diagnosis of glaucoma and cataracts. The patient was in good health until two weeks prior to admission when she noted a black cloud in her visual field in the top central area. The cloud gradually chang...Occipital Lobe; Visual Hallucinations; Release Hallucinations; Charles Bonnet Syndrome
866 Myasthenia Gravis (Guest Lecture)Shirley H. Wray, MD, PhD, FRCPThe patient is a 46 year old woman who presented in July 1977 with horizontal double vision lasting two weeks. Three weeks later the left upper eyelid started to droop and by the end of the day the eye was closed. She had no ptosis of the right eye and no generalized fatigue. She consulted an intern...Unilateral Ptosis; Unilateral Lid Retraction; Myasthenic Lid Twitch; External Ophthalmoplegia; Ocular Myasthenia Gravis; Tensilon Test; Thymolipoma; Generalized Myasthenia Gravis; Unilateral Myasthenia Gravis; Myasthenic Ptosis; Lid Retraction; Lid Twitch
867 Bilateral PtosisShirley H. Wray, MD, PhD, FRCPThis case, previously reported in 2007, is published courtesy of John Newsom-Davis, M.D., FRCP, FRS, CBE. Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford. This patient was unusual in presenting in early childhood and the development of persistent facial muscle and tongue ...Bilateral Ptosis; Full Eye Movements; Facial Weakness; Tongue Atrophy; MuSK Antibody Myasthenia Gravis
868 Ocular Myasthenia Gravis (Guest Lecture)Shirley H. Wray, MD, PhD, FRCPSee also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/264, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/337, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/332, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/265, and http://content.lib.utah.edu/cd...Unilateral ptosis; Positive tensilon test; Ocular Myasthenia Gravis; Unilateral Myasthenia Gravis; Ptosis -- Myasthenic Pseudo-internuclear Ophthalmoplegia; Bilateral Weakness of Adduction; Tensilon Test; Bilateral Myasthenia Gravis; Internuclear Ophthalmoplegia; Familial Myasthenia Gravis;...
869 Horizontal Gaze PalsyShirley H. Wray, MD, PhD, FRCPThis 56 year old woman with known adenocarcinoma of the breast presented with the recent onset of horizontal diplopia and deviation of her left eye inwards. Her oncologist referred her for a neuro-ophthalmic evaluation. This 56 year old woman with known adenocarcinoma of the breast presented with th...Unilateral Horizontal Gaze Palsy; Esotropia; Fascicular Sixth Nerve Palsy; Horizontal Gaze Evoked Nystagmus; Normal Convergence; Horizontal Oculocephalic Reflexes Absent; Facial Palsy (Bell's Palsy); Abducens Nuclear Lesion; Pontine Metastasis; Adenocarcinoma of the Breast; Unilateral Sixth Nerve Pa...
870 Chiari I MalformationShirley H. Wray, MD, PhD, FRCPSee also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/295, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/323, and http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/61Downbeat Nystagmus; Oscillopsia; Chiari-1 Malformation; Primary Position Downbeat Nystagmus; Vertical Saccadic Dysmetria; Horizontal Saccadic Dysmetria; Ataxia; Dysmetria; Chiari Malformation
871 Carotid Cavernous Fistulas (PowerPoint)AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietyThis 76-year-old woman has a 7-month history of redness and pressure sensation in both eyes that is worse in the morning. She has noted intermittent horizontal diplopia during this time. Angiography demonstrated a right dural cavernous sinus fistula, which was successfully occluded with direct injec...Dural Arteriovenous Malformation; Carotid Cavernous Fistulas
872 Leber's Optic Neuropathy (PowerPoint)AAO/NANOS - American Academy of Ophthalmology / North American Neuro-Ophthalmology SocietySeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.Leber's Optic Neuropathy
873 Mitochondrial MyopathyShirley H. Wray, MD, PhD, FRCPA PowerPoint slideshow describing the condition.Bilateral Progressive External Ophthalmoplegia (PEO); Bilateral Ptosis; Cerebellar Degeneration with Ataxia; Complete External Ophthalmoplegia; External Ophthalmoplegia Affecting Upgaze; Facial Weakness; Kearns-Sayre Syndrome; Mitochondrial Myopathy; Normal Pupils; PEO plus Atypical Retinitis Pigm...
874 Transient Monocular Blindness (Guest Lecture)Shirley H. Wray, MD, PhD, FRCPSee also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/293 and http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/96Retinal Emboli; Transient Monocular Blindness; Ocular Stroke; Transient; Transient Visual Loss; Sunlight Provoked Transient Monocular Blindness; Low Pressure Retinopathy; Ipsilateral Internal and External Carotid Occlusive Disease; Ischemic Eye Syndrome; Retinal Stroke; Ocular Ischemic Sy...
875 Congenital Horizontal Gaze Palsy, Progressive ScoliosisShirley H. Wray, MD, PhD, FRCPThe patient is an 8 year old boy with a rare autosomal recessive disorder characterized by congenital absence of conjugate horizontal eye movements preservation of vertical gaze and convergence and progressive scoliosis (HGPPS) developing in childhood. The child was referred to Dr. Cogan with a diag...Congenital Horizontal Gaze Palsy; Progressive Scoliosis; Mutation of the ROBO 3 Gene on Chromosome 11q23-q25; Congenital Cranial Disinnervation Syndrome; Mobius Syndrome
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