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TitleCreatorDescriptionSubject
1 Neuro-Ophthalmology of Multiple SclerosisEmily Sun, Medical Student; Amanda Henderson, MDMultiple Sclerosis (MS) is the most common neurological disease in young people with an average age of onset between 15 and 35 years old. MS is an autoimmune inflammatory condition that causes demyelinating lesions in the CNS. The diagnosis is clinical, but MRI is typically used to support the diagn...Multiple Sclerosis; Optic Neuritis; Uveitis; Internuclear Ophthalmoplegia; Nystagmus; Steroids; Demyelinating; Autoimmune
2 Illustrations of the Afferent Visual Pathway and Concepts Surrounding Trans-Synaptic Neuroaxonal Degeneration in the Visual Pathway in Multiple SclerosisOlwen C. Murphy; Peter A. Calabresi; Shiv SaidhaImage 1 title: Functionally-eloquent organization of the afferent visual pathway; Image 1 description: The afferent visual pathway is a sensory pathway comprised of 3 neurons. The 1st order neurons are the shortest neurons in the pathway and are entirely unmyelinated. The cell bodies of the 1st orde...Optic Neuritis; Multiple Sclerosis; Neuroaxonal Degeneration; Trans-synaptic Degeneration; Visual Pathway; Functional Eloquence
3 Multiple Sclerosis Treatment StrategiesJohn Pula, MDSlideshow exploring current treatment of multiple sclerosis.Multiple Sclerosis; Multiple Sclerosis Treatment
4 Chiasmal Neuritis in Multiple SclerosisKathleen B. Digre, MD; James J. Corbett, MDSlideshow describing condition.Multiple Sclerosis
5 Multiple SclerosisShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Bilateral Lid Nystagmus; Horizontal Saccadic Dysmetria; Jerk Oscillations; Lid Nystagmus; Multiple Sclerosis; Primary Position Upbeat Nystagmus; Rotary Nystagmus; Saccadic Dysmetria; Saccadic Pursuit; Square Wave Jerks; Torsional Nystagmus; Upbeat Nystagmus
6 Brain MRI in Multiple Sclerosis (Guest Lecture)Anne G. Osborn, MDThe patient is a 25 year old woman who was in excellent health until 4 days prior to admission when she noted blurred vision and horizontal double vision on lateral gaze to right and left. Past History: Negative for strabismus as a child. No previous episodes of transient neurological symptoms. Fami...Bilateral Internuclear Ophthalmoplegia; Abducting Nystagmus; Normal Convergence; Gaze Evoked Upbeat Nystagmus; Gaze Evoked Downbeat Nystagmus; Saccadic Dysmetria; Multiple Sclerosis; Horizontal Saccadic Dysmetria
7 One and a Half SyndromeShirley H. Wray, MD, PhD, FRCPThis 44 year old woman presented in 1973 with an acute attack of optic neuritis in the right eye that fully recovered after a course of ACTH therapy. In 1991, 18 years later, she developed unsteadiness of gait, "walking like a chicken", stiff legs that jerked spontaneously in bed at night, and numbn...Unilateral Internuclear Ophthalmoplegia; Unilateral Horizontal Gaze Palsy; Upbeat Nystagmus on Upgaze; Convergence Normal; Fisher's One-and-a-Half Syndrome; Uhthoff's Symptom; Multiple Sclerosis; Unilateral Horizontal Gaze Palsy Demyelination; Gaze Evoked Upbeat Nystagmus; Abducting Nystagmus
8 Pendular OscillationsShirley H. Wray, MD, PhD, FRCPThis 37 year old woman has had progressive multiple sclerosis (MS) affecting the cerebellum and brainstem for 6 years. Neurological examination: Titubation Dysarthria Incoordination of the extremities Ataxic gait Spastic paraparesis with generalized hyperreflexia and extensor plantar responses. Neur...Pendular Horizontal Oscillations; Left Beating Nystagmus; Obtrusive Saccades; Bilateral Gaze Evoked Nystagmus; Saccadic Dysmetria; Oscillopsia; Titubation; Ataxia; Multiple Sclerosis; Primary Position Horizontal Nystagmus; Gaze Evoked Horizontal Nystagmus; Horizontal Saccadic Dysmetria
9 Bilateral Internuclear OphthalmoplegiaShirley H. Wray, MD, PhD, FRCPThis patient was seen at the Yale Eye Center at the age of 37. She had a long history of multiple sclerosis. At age 22, she had an acute attack of optic neuritis in the left eye which recovered fully within three weeks. Some months later she had a recurrent episode in the same eye, which also recove...Bilateral Internuclear Ophthalmoplegia; Pendular Horizontal Oscillations; Lid Nystagmus; Upbeat Nystagmus; Botulinum Toxin Therapy; Multiple Sclerosis; Horizontal Pendular Nystagmus; Gaze Evoked Upbeat Nystagmus; Abducting Nystagmus
10 Downbeat Nystagmus PANShirley H. Wray, MD, PhD, FRCPThis patient carries a diagnosis of multiple sclerosis. See also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/317Downbeat Nystagmus; Periodic Alternating Nystagmus; Multiple Sclerosis; Primary Position Downbeat Nystagmus
11 Multiple SclerosisShirley H. Wray, MD, PhD, FRCPThe patient is a 56 year old woman who presented in 1982, at the age of 48, with a one week history of painless loss of vision in the left eye. Past History: Negative for a previous attack of optic neuritis or transient neurological symptoms. Family History: Negative for CNS disease Neuro-ophthalmol...Upbeat Nystagmus; Lid Nystagmus; Square Wave Jerks; Jerk Oscillations; Rotary Nystagmus; Saccadic Pursuit; Saccadic Dysmetria; Multiple Sclerosis; Bilateral Lid Nystagmus; Primary Position Upbeat Nystagmus; Torsional Nystagmus; Horizontal Saccadic Dysmetria
12 Multiple Sclerosis LateropulsionShirley H. Wray, MD, PhD, FRCPThis 44 year old woman has a diagnosis of Multiple Sclerosis. See also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/281Deviation of the Eyes Under Closed Lids; Lateropulsion; Multiple Sclerosis
13 Brain MRI in Multiple SclerosisAnne G. Osborn, MDSlideshow describing condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Downbeat Nystagmus; Horizontal Pendular Nystagmus; Horizontal Saccadic Dysmetria; Lid Nystagmus; Multiple Sclerosis; Normal Convergence; Oscillopsia; Pendular Horizontal Oscillations; Saccadic Dysmetri...
14 Pendular Horizontal OscillationsShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Ataxia; Bilateral Gaze Evoked Nystagmus; Gaze Evoked Horizontal Nystagmus; Horizontal Saccadic Dysmetria; Left Beating Nystagmus; Multiple Sclerosis; Obtrusive Saccades; Oscillopsia; Pendular Horizontal Oscillations; Primary Position Horizontal Nystagmus; Saccadic Dysmetria; Titubation
15 Bilateral Internuclear OphthalmoplegiaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Upbeat Nystagmus; Horizontal Pendular Nystagmus; Lid Nystagmus; Multiple Sclerosis; Pendular Horizontal Oscillations; Upbeat Nystagmus
16 Downbeat Nystagmus PANShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Downbeat Nystagmus; Periodic Alternating Nystagmus; Multiple Sclerosis
17 Multiple Sclerosis 2008: Bench to Bedside….and Back Again, The Raymond Adams LectureStephen L. Hauser, MDSlideshow describing condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Downbeat Nystagmus; Horizontal Pendular Nystagmus; Horizontal Saccadic Dysmetria; Lid Nystagmus; Multiple Sclerosis; Normal Convergence; Oscillopsia; Pendular Horizontal Oscillations; Saccadic Dysmetri...
18 One and a Half SyndromeShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Abducens Nuclear Lesion; Abducting Nystagmus; Cavernous Angioma; Convergence Absent; Convergence Normal; Esotropia; Facial Palsy; Facial Weakness; Fisher's One-and-a-Half Syndrome; Gaze Evoked Upbeat Nystagmus; Multiple Sclerosis; Pendular Vertical Oscillations; Pontine Hemorrhage; Pontine Infarct;...
19 Multiple Sclerosis LateropulsionShirley H. Wray, MD, PhD, FRCPPowerPoint slideshow describing the condition.Deviation of the Eyes Under Closed Lids; Lateropulsion; Multiple Sclerosis
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