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CreatorTitleDescriptionSubjectDate
551 Gardner, Reed M.Implementation of Medical Information Bus (MIB) at LDS HospitalBiomedical Informatics1988
552 Warner, Homer R.Implementation of Practice in a Clinical Setting Using a Computerized Knowledge Base (ILIAD)Biomedical Informatics1993
553 Gardner, Reed M.Improved Perioperative Antibiotic Use and Reduced Surgical Wound Infection Through Use of Computer Decision AnalysisBiomedical Informatics1989
554 Narus, Scott P.Improving access to longitudinal patient health information within an emergency departmentWe designed and implemented an electronic patient tracking system with improved user authentication and patient selection. We then measured access to clinical information from previous clinical encounters before and after implementation of the system. Clinicians accessed longitudinal information for...2012-01-01
555 Pepper, Ginette A.Improving geriatric drug therapy.Healthcare professional and society in general harbor ambivalent beliefs about drug therapy. Most of us anticipate that drugs will eventually control, or even cure many age-related diseases. On the other hand, there is a growing unease about the hazards of medications, which range from minor discomf...Older people1987-10
556 Baehr, WolfgangIn vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteriaWe investigated the specificity of CAAX box-related isoprenylation of rod photoreceptor cGMP phosphodiesterase (PDE) subunits expressed in bacteria and the consequences of this modification on rod disk membrane association. Full-length cDNA sequences of the alpha and beta subunits of mouse PDE, inse...Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data1992
557 Capecchi, Mario R.In vivo and in vitro tissue-specific expression of green fluorescent protein using the cre-lox system in mouse embryonic stem cells.Embryonic stem cells (ES) are pluripotent and may therefore serve as a source for the generation of specific cell types required for future therapies based on cell replacement. The isolation of defined cell populations from a certain lineage or tissue is a prerequisite for the analysis of the potent...Animals; Cell Differentiation; Cells, Cultured; Gene Transfer Techniques; Mice, Transgenic2005-10-23
558 Frederick, Jeanne M.Inactivity of human β,β-carotene-9′, 10-′dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigmentThe macula of the primate retina uniquely concentrates high amounts of the xanthophyll carotenoids lutein, zeaxanthin, and meso-zeaxanthin, but the underlying biochemical mechanisms for this spatial- and species-specific localization have not been fully elucidated. For example, despite abundant reti...2014-01-01
559 Couldwell, William T.Increased invasive capacity of connexin43-overexpressing malignant glioma cellsObject. Malignant glioma cells, similar to astrocytes, express connexin43 (Cx43) universally but at widely varied levels. Data from previous studies have demonstrated that malignant glioma cells form functional gap junction channels among themselves as well as with astrocytes and that such a communi...2003-12
560 Couldwell, William T.Increasing exposure of the petrous internal carotid artery for revascularization using the transzygomatic extended middle fossa approach: a cadaveric morphometric studyWhen internal carotid artery (ICA) sacrifice is planned in the management of difficult tumors or aneurysms at the cranial base, the petrous ICA may be a useful site for anastomosis for interpositional vascular bypass. However, exposure of the artery and performing an anastomosis in this region may...Revascularization; Internal carotid artery; Cranial base tumors; Giant aneurysms; Interpositional bypass; Surgical approach; Middle fossa2006
561 Gardner, Reed M.Indewlling Arterial Catheters (Letter)Biomedical Informatics1974
562 Warner, Homer R.Indicator Dispersion in the CirculationBiomedical Informatics1965
563 Hobbs, Maurine R.; Granger, Donald LeeInducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic populationPolymorphisms in the inducible nitric oxide synthase gene (NOS2) promoter have been associated with clinical outcome from malaria. These include a CCTTT repeat (CCTTTn) 2.5 kilobases upstream from the NOS2 transcription start site, and two single nucleotide substitutions: G-->C at position -954 (G-9...Papua New Guinea; Oceanic Ancestry Group; Repetitive Sequences, Nucleic Acid2003
564 Kestle, John R. W.; Simon, Tamara DanielleInfection rates following initial cerebrospinal fluid shunt placement across pediatric hospitals in the United StatesObject. Reported rates of CSF shunt infection vary widely across studies. The study objective was to determine the CSF shunt infection rates after initial shunt placement at multiple US pediatric hospitals. The authors hypothesized that infection rates between hospitals would vary widely even after ...Shunt placement; Pediatric neurosurgery2009
565 Couldwell, William T.Inflammatory pseudotumor of the cavernous sinus and skull baseInflammatory pseudotumor is a non-neoplastic process of unknown etiology characterized by a proliferation of connective tissue with an inflammatory infiltrate. Intracranial inflammatory pseudotumors classically involve the cavernous sinus but can also occur in the supratentorial or infratentorial c...Intracranial neoplasm; Pseudotumor; Skull base2006
566 Warner, Homer R.Influence of Hypoxia on the Pulmonary Circulation of Nonnarcotized DogsBiomedical Informatics1954
567 Wittwer, Carl T.Influence of PCR reagents on DNA polymerase extension rates measured on real-time PCR instrumentsBACKGROUND: Radioactive DNA polymerase activity methods are cumbersome and do not provide initial extension rates. A simple extension rate assay would enable study of basic assumptions about PCR and define the limits of rapid PCR. METHODS: A continuous assay that monitors DNA polymerase extension us...2014-01-01
568 Gesteland, Raymond F.; Atkins, John F.Influence of the stacking potential of the base 3' of tandem shift codons on -1 ribosomal frameshifting used for gene expressionTranslating ribosomes can shift reading frame at specific sites with high efficiency for gene expression purposes. The most common type of shift to the 1 frame involves a tandem realignment of two anticodons from pairing with mRNA sequence of the form X XXY YYZ to XXX YYY Z where the spaces indicate...1 frameshifting; 39 context effect; Codon anticodon interaction; Escherichia coli ; Recoding; tRNALys; XXXY YYZ frameshift motifs2002
569 Warner, Homer R.Information Systems and Patient CareBiomedical Informatics1982
570 Couldwell, William T.Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic applicationProtein kinase C (PKC) is an enzyme involved in the regulation of cellular growth, proliferation, and differentiation in a number of tissues including the anterior pituitary, in which it is also believed to play a role in hormone secretion. Protein kinase C activity and expression have been found to...Apoptosis; Hypericin; Pituitary adenoma; Protein kinase C1996
571 Couldwell, William T.Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C systemThe protein kinase-C (PKC) second messenger system contributes to regulation of cell growth and differentiation. This study was undertaken to examine the effects of modulators of the PKC enzyme system on the state of differentiation and proliferation rates of human gliomas in vitro. The administrat...Protein kinase C; Phorbol ester; Cell proliferation; Tumor cell growth; Astrocyte; Glioma; Immunohistochemistry1990
572 Frederick, Jeanne M.Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis.Metalloendoprotease activity was identified in retinal homogenates using a synthetic fluorogenic metalloendoprotease substrate and specific metalloendoprotease inhibitors. The requirement of metalloendoprotease activity in neurotransmitter release was examined during the depolarization-induced relea...Neuromuscular Junction; Neurotransmitter Agents; Membrane Fusion1984
573 Couldwell, William T.Initial experience related to the use of the Cosman-Roberts-Wells stereotactic instrumentInitial experience with a new arc-radius design of stereotactic frame that interfaced with the existing components of the Brown-Roberts-Wells instrument is reported. Over a 6-month period, 32 procedures were performed on 23 males and nine female patients (mean age 32 years); these included 27 ster...Image-directed stereotaxis; Stereotactic instrument; Cosman-Roberts-Wells stereotaxy1990
574 Capecchi, Mario R.Initiation of E. coli proteins.Recent experiments and theoretical arguments suggest that formylmethionyl sRNA is employed as an initiator of protein synthesis. Studies also indicated that other phage proteins synthesized in the in vitro system were initiated with formylmethionine. These observations provided a basis for believin...Alanine; Chromatography, Paper; Dipeptides1966-06
575 Gardner, Reed M.Instrumentation for Computerized Heart CatheterizationBiomedical Informatics1971
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