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CreatorTitleDescriptionSubjectDate
476 Warner, Homer R.The HELP SystemBiomedical Informatics1982
477 Warner, Homer R.The HELP SystemBiomedical Informatics1984
478 Warner, Homer R.The HELP System as a Tool for Monitoring Physician Prescribing PatternsBiomedical Informatics1980
479 Warner, Homer R.The HELP System Development ToolsBiomedical Informatics1989
480 Warner, Homer R.The HELP System for Medical Decision MakingBiomedical Informatics1974
481 Warner, Homer R.The HELP System: A System for Clinical Decision-MakingBiomedical Informatics1986
482 Warner, Homer R.HELP/PATHLAB Integration - A Decade of Experience Using an Expert System Interfaces to a Clinical Laboratory SystemBiomedical Informatics1985
483 Warner, Homer R.HELP: A Computerized Medical Decision Support SystemBiomedical Informatics1986
484 Warner, Homer R.HELP: A Medical Information System With Decision Making CapabilityBiomedical Informatics1985
485 Couldwell, William T.; Schloesser, Peter E.Hemorrhage from moyamoya-like vessels associated with a cerebral arteriovenous malformationThe authors describe a case of subarachnoid hemorrhage from moyamoya-like vessels associated with an arteriovenous malformation (AVM) in a 44-year-old Hispanic man who presented with severe headache. The AVM was located in the left parietal lobe and the ipsilateral middle cerebral artery was occlude...Moyamoya-like vessels; Arteriovenous malformation; Ischemia MeSH: Arteriovenous malformations2004
486 Couldwell, William T.Hemorrhagic and nonhemorrhagic Rathke cleft cysts mimicking pituitary apoplexyObject. Rathke cleft cysts (RCCs) are infrequently symptomatic, and apoplexy is one of the most unusual presentations. Only a few cases of apoplexy associated with RCCs have been reported, and their clinical, imaging, surgical, and pathological features are poorly understood. In the cases that have ...2008-01-01
487 Liew, Michael; Erali, Maria; Page, Sam; Hillyard, David R.; Wittwer, Carl T.Hepatitis C genotyping by denaturing high-performance liquid chromatographyDetermination of the hepatitis C virus (HCV) genotype for infected patients increasingly has become accepted as the standard of care. Genotype assignment helps in assessing disease prognosis and assists in establishing the appropriate duration of treatment. The great genetic diversity of HCV, with 1...Base Sequence; 5' Untranslated Regions; Genotype; Hepacivirus; Molecular Sequence Data2004-01
488 Teerlink, Craig CarlHeritability of facial appearance2012
489 Dwight, Zachary LawrenceHeterozygote PCR product melting curve predictionMelting curve prediction of PCR products is limited to perfectly complementary strands. Multiple domains are calculated by recursive nearest-neighbor thermodynamics. However, the melting curve of an amplicon containing a heterozygous single nucleotide variant (SNV) after PCR is the composite of four...2014-01-01
490 Zhang, KangHeterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalitiesPURPOSE: The PITX3 gene, which codes for a homeobox bicoidlike transcription factor is responsible for dominant cataract and anterior segment mesenchymal dysgenesis in humans. In the current study, a family with autosomal dominant posterior polar cataract (PPC) and a PITX3 mutation that cosegregates...Chromosomes, Human, Pair 10; Homozygote; Lod Score2006
491 Del Fiol, GuilhermeHeuristics in managing complex clinical decision tasks in experts decision makingBackground: Clinical decision support is a tool to help experts make optimal and efficient decisions. However, little is known about the high level of abstractions in the thinking process for the experts. Objective: The objective of the study is to understand how clinicians manage complexity while...2014-01-01
492 Huang, Lin EricHIF-1? mediates tumor hypoxia to confer a perpetual mesenchymal phenotype for malignant progressionAlthough tumor progression involves genetic and epigenetic alterations to normal cellular biology, the underlying mechanisms of these changes remain obscure. Numerous studies have shown that hypoxia-inducible factor 1? (HIF-1?) is overexpressed in many human cancers and up-regulates a host of hypoxi...
493 Capecchi, Mario R.High efficiency transformation by direct microinjection of DNA into cultured mammalian cells.Direct microinjection of DNA by glass micropipettes was used to introduce the Herpes simplex virus thymidine kinase gene into cultured mammalian cells. When DNA was delivered directly into the nuclei of LMTK-, a mouse cell line deficient in thymidine kinase activity, 50--100% of the cells expressed ...Cell Nucleus; Cytoplasm; DNA, Viral; Microinjections; Recombination, Genetic1980-11-22
494 Kestle, John R. W.High incidence of tumor dissemination in myxopapillary ependymoma in pediatric patientsP Myxopapillary ependymomas (MPEs) have historically been thought to be benign tumors occurring most frequently in adults. Only 8 to 20% of these tumors occur in the first two decades of life, making this tumor a rarity in pediatric neurosurgery. Five patients with intraspinal MPEs were treated by t...2005-01
495 Kestle, John R. W.High incidence of tumor dissemination in myxopapillary ependymoma in pediatric patientsP Myxopapillary ependymomas (MPEs) have historically been thought to be benign tumors occurring most frequently in adults. Only 8 to 20% of these tumors occur in the first two decades of life, making this tumor a rarity in pediatric neurosurgery. Five patients with intraspinal MPEs were treated by t...Myxopapillary ependymoma; Tumor dissemination2005
496 Warner, Homer R.High-Density Medical Data Management by ComputerBiomedical Informatics1970
497 Thomas, Kirk R.; Capecchi, Mario R.High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors.Mutations were targeted to the Hprt locus in murine embryonic stem cells by using sequence replacement vectors. When the vector was designed such that the mutated sequences were flanked on both sides by several kilobases of DNA homologous to the target locus, replacement of chromosomal sequences wit...Drug Resistance; Gene Rearrangement; Gentamicins1992-07
498 Couldwell, William T.History and evolution of transsphenoidal surgeryInitial attempts at transcranial approaches to the pituitary gland in the late 1800s and early 1900s resulted in a mortality rate that was generally considered prohibitive. Schloffer suggested the use of a transsphenoidal route as a safer, alternative approach to the sella turcica. He reported the f...Neurosurgical history; Transsphenoidal surgery; Pituitary tumor2001
499 Warner, Homer R.History of Medical Informatics at UtahBiomedical Informatics1990
500 Capecchi, Mario R.Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase.We have examined the effect of cell cycle position on homologous recombination between plasmid molecules coinjected into synchronized rat fibroblasts. Recombination activity was found to be low in G1 and to rise 10- to 15-fold, peaking in early to mid-S phase.Cell Line; Kinetics; Plasmids1986-06
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