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1 Hawkes, KristenA reappraisal of grandmothering and natural selectionKachel et al. [1] conclude from simulations of their agent-based model that fitness benefits from helpful grandmothers do not select for increased longevity. We studied their assumptions and model, ran further simulations and found flaws that are fatal to their test. Here, we explain four problems a...2011-01-01
2 Gerig, GuidoAbnormal brain synchrony in down syndromeDown Syndrome is the most common genetic cause for intellectual disability, yet the pathophysiology of cognitive impairment in Down Syndrome is unknown. We compared fMRI scans of 15 individuals with Down Syndrome to 14 typically developing control subjects while they viewed 50 min of cartoon video c...2013-01-01
3 Awasthi, Manu; Nellans, David W.; Sudan, Kshitij; Balasubramonian, RajeevABP : predictor based management of DRAM row buffersDRAM accesses are costly, especially in multicore systems. Future CMPs will run a mixed load of workloads/threads. Destructive interference at memory controller, spatio-temporal locality lost! DRAM row-buffer hits are least expensive, row-conflicts are most. Randomized memory access patterns re...2010-10-06
4 Hawkes, KristenAffluent hunters? Some comments in light of the Alyawara caseOur recent analysis (O'Connell and Hawkes in press) of plant food collecting among the Alyawara, a central Australian hunting group, shows that the cost of subsistence is sometimes quite high, far higher than the current conven. tional wisdom regarding hunters would suggest. We infer from available ...1981-01-01
5 Hawkes, KristenAge-related decline in ovarian follicle stocks differ between chimpanzee (Pan troglodytes) and humansSimilarity in oldest parturitions in humans and great apes suggests that we maintain ancestral rates of ovarian aging. Consistent with that hypothesis, previous counts of primordial follicles in postmortem ovarian sections from chimpanzees (Pan troglodytes) showed follicle stock decline at the same ...2015-01-01
6 Hall, Eric S.Aiding clinicians through summarization of perinatal dataExploratory analysis has focused on developing summarized views of monitor-captured perinatal data to support adherence to established clinical protocols. In addition to facilitating rapid access to significant clinical trends and reducing subjective interpretation of monitor-captured data, combini...Perinatal data; Perinatal care; Trapeze Interactive Poster2009-09-23
7 Yanowitz, Frank G.Alan E. Lindsay ECG Learning Center in CyberspaceAn interactive ECG tutorial representing an introduction to clinical electrocardiography.Electrocardiography1996-09-01
8 Gerig, GuidoAsymmetrical ventricular enlargement in Parkinsons DiseaseBackground-A recent case report suggested the presence of asymmetrical lateral ventricular enlargement associated with motor asymmetry in Parkinson's disease (PD). The current study explored these associations further. Methods-Magnetic resonance imaging (3T) scans were obtained on 17 PD and 15 healt...Structural magnetic resonance imaging; Semi-automatic segmentation; Lateral ventricular volume; Motor asymmetry; Parkinson's disease2007-01-01
9 Gerig, GuidoAutomatic and robust computation of 3D medial models incorporating object variabilityAbstract. This paper presents a novel processing scheme for the automatic and robust computation of a medial shape model which represents an object population with shape variability. The sensitivity of medial descriptions to object variations and small boundary perturbations are fundamental problems...2003-01-01
10 DuVall, Scott L.Automatic, near real-time reporting of communicable diseases via web syndicationReal-time, automatic surveillance of reportable diseases remains an obstacle in Public Health. Reports are generated manually by healthcare provided and sent to local or state public health offices. Web syndication is the way to publish and transmit information to subscribed users. This is typicall...Web syndication; Electronic reporting; Real-time reporting; Trapeze Interactive Poster2009-09-23
11 Gerig, GuidoBrain lesion segmentation through physical model estimationSegmentations of brain lesions from Magnetic Resonance (MR) images is crucial for quantitative analysis of lesion populations in neuroimaging of neurological disorders. We propose a new method for segmenting lesions in brain MRI by inferring the underlying physical models for pathology. We use the r...Magnetic resonance (MR) images; Neurological disorders; Diffusion tensor imaging (DTI).2008-01-01
12 Hawkes, KristenBrief communication: adrenal androgens and aging: female chimpanzees (Pan troglodytes) compared with womenOvarian cycling continues to similar ages in women and chimpanzees yet our nearest living cousins become decrepit during their fertile years and rarely outlive them. Given the importance of estrogen in maintaining physiological systems aside from fertility, similar ovarian aging in humans and chimpa...Dehydroepiandrosterone sulfate; Senescence; Aging rates; Human longevity2013-01-01
13 Arlitsch, KenningCollaboration and partnerships: opportunities aboundPowerPoint presentation describing some of the digital collection building partnerships of the University of Utah. Major covered projects include the Utah Digital Newspapers Program, Mountain West Digital Library, Western Waters Digital Library, and the Utah Artists Project, among others.Digital collections; Electronic libraries; Cooperative collection building2006-01-22
14 Gerig, GuidoDiffusion imaging quality control via entropy of principal direction distributionDiffusion MR imaging has received increasing attention in the neuroimaging community, as it yields new insights into the microstructural organization of white matter that are not available with conventional MRI techniques. While the technology has enormous potential, diffusion MRI suffers from a uni...Diffusion magnetic resonance imaging; Diffusion tensor imaging; Quality assessment; Entropy2013-01-01
15 Frey, Lewis J.Enhancing caBIG™ workflow for multi-tier distributionIntroduction caBIG™ Integration caBIG™ provides a GRID based application environment with data abstraction and vocabulary services, workflow management and a security framework. Sensor Abstraction Interface It is proposed to provide a sensor abstraction interface, using caDSR, enabling caBIG...caBIG; Sensor abstraction interface; Multi-tier distribution; Trapeze Interactive Poster2009
16 Hawkes, KristenEvaluating grandmother effectsWomen who have outlived child-bearing have long been described as post-reproductive. But contributions they make to the survival or fertility of their descendants enhance the reproduction of their genes. Consequently natural selection affects this characteristic stage of human life history. Grandmot...Human life history; Historical demography; Human longevity2009-01-01
17 Gerig, GuidoEvaluation of brain MRI alignment with the Robust Hausdorff Distance MeasuresWe present a novel automated method for assessment of image alignment, applied to non-rigid registration of brain Magnetic Resonance Imaging data (MRI) for image-guided neurosurgery. We propose a number of robust modifications to the Hausdorff distance (HD) metric, and apply it to the edges recovere...Magnetic resonance imaging (MRI)2008-01-01
18 Gerig, GuidoFiber tract-oriented statistics for quantitative diffusion tensor MRI analysisDiffusion tensor imaging (DTI) has become the major modality to study properties of white matter and the geometry of fiber tracts of the human brain. Clinical studies mostly focus on regional statistics of fractional anisotropy (FA) and mean diffusivity (MD) derived from tensors. Existing analysis t...Diffusion tensor interpolation, Diffusion tensor statistics, DTI analysis, Fiber tract modeling2006-01-01
19 Gerig, GuidoFrontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 monthsElucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy tha...Joint attention; DTI; Amygdala; Uncinate fasciculus; Infancy; Development2013-01-01
20 Arlitsch, KenningFuture leaders of research libraries: what are they thinking?Summarizes the initial findings of survey research conducted with 175 future library leaders. Respondents were asked whether they are satisfied with their organizational culture and management, whether organizational culture limits thier effectiveness, and whether respondents are consideringleaving...Future leaders2009-04-06
21 Hawkes, KristenThe grandmother effectWhy do women live long past the age of child-bearing? Contrary to common wisdom, this phenomenon is not new, and is not due to support for the elderly. Rather, grannies have a lot to offer their grandchildren.2004-01-01
22 Hawkes, KristenGrandmother effects, heterogeneity, and the evolution of human aging: guidance from human-chimpanzee comparisonsIn the first paper to present formal theory explaining that senescence is a consequence of natural selection, W. D. Hamilton concluded that human postmenopausal longevity results from the contributions of ancestral grandmothers to the reproduction of their relatives. A grandmother hypothesis, subseq...Evolution of senescence; Heterogeneity of frailty; Human life history; Menopause; Human aging2010-01-01
23 Hawkes, KristenGrandmothers and the evolution of human longevity: a review of findings and future directionsWomen and female great apes both continue giving birth into their forties, but not beyond. However humans live much longer than other apes do.[1] Even in hunting and gathering societies, where the mortality rate is high, adult life spans average twice those of chimpanzees, which become decrepit duri...Life history evolution; Senescence; Cooperative child rearing; Infant psychology; Male-male competition2013-01-01
24 Gerig, GuidoGroup analysis of DTI fiber tract statistics with application to neurodevelopmentDiffusion tensor imaging (DTI) provides a unique source of information about the underlying tissue structure of brain white matter in vivo including both the geometry of major fiber bundles as well as quantitative information about tissue properties represented by derived tensor measures. This paper...Diffusion tensor imaging; Registration; Tract modeling; Neurodevelopment; Statistical modeling2009-01-01
25 Dennis, Sharon E.; Uijtdehaage, Sebastian; Candler, C.Health Education Assets Library (HEAL)The Health Education Assets Library (HEAL) is a digital library that provides freely accessible digital teaching resources of the highest quality that meet the needs of today's health sciences educators and learners.HEAL; Health Education Assets Library2000
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