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Creator | Title | Description | Subject | Date |
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Arave, Rowan A. | AKT1 activation promotes the development of melanoma metastasis | Metastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT (or protein kinase B) signaling in human melanoma metastases led to the evaluation of the effect of activated AKT1 expression in non-metastatic BRAFV600E/cyclin dependent kinase inhibitor 2a nu... | Melanoma - Genetics - Research; Metastasis - Genetics - Research; Biochemistry; Genetics | 2015-12 |
2 |
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Arnoholt, Alayna | An analysis on the influence of anxiety in post error slowing | Anxiety disorders are among the most common mental disorders and affect 15.7 million Americans each year (Lépine, 2002, p. 4). Anxiety is associated with reduced productivity, physical distress, and other diseases such as depression. Anxiety could also be influential in error response (Compton et a... | | 2021 |
3 |
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Zhu, Judy | Analysis of the pH-dependent equilibrium relationship between the guanine oxidation products 5-guanidinohydantoin and iminoallantoin | Oxidation of 2'-deoxyguanosine (dG) results in the major two-electron product 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG) that can undergo further oxidation to other products. One such product is 5-guanidinohydantoin (dGh) that is highly mutagenic and has been found in vivo. The ring architecture of d... | Oxidation; guanine oxidation products; 5-guanidinohydantoin; Iminoallantoin; Equilibrium relationship | 2015-05 |
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Edwards, Jennifer Lynn | Application of a TBHP-mediated Wacker-type oxidation to internal alkenes | The Wacker oxidation allows access to methyl ketones from terminal alkenes. This transformation is important for industrial, synthetic, and medicinal chemists, as carbonyls are present in many natural and pharmaceutical products. With the carbonyl, a wide variety of reactions become available, such ... | Wacker-type oxidatioin - Research; TBHP | 2013-05 |
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Pecchia-Bekkum, Annika | Applications of controlled DNA assembly and disassembly in biosensing and responsive drug delivery | Deoxyribonucleic acid (DNA) provides many exciting functions outside of simply encoding genetic information. Herein, we report two techniques to control the assembly and disassembly of nucleic acids. Within these techniques, DNA is used as a programmable material for biosensing and drug delivery. In... | Nucleic acids - Biotechnology | 2013-08 |
6 |
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Burga, Carlos Alberto | Binary superlattices of semiconductor nanocrystals : a path towards possible high-temperature superconductivity | This thesis provides a platform to experimentally test Dr. Daniel Mattis' theoretical work on the possible superconductive behavior of nanostructured intrinsic semiconductors1-2. The theoretical work hinged on the nano-scale architecture of semiconductors. Therefore, using various types of semicondu... | Semiconductor nanocrystals; Superconductivity; Superlattices as materials | 2013-05 |
7 |
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Rose, Steven | Biofuel cells for self powered arsenic detection | Research in the Minteer group has centered on procedures for immobilizing enzymes and organelles on carbon electrodes for use in sensory and fuel cell applications. Similar strategies have been used to prepare a series of electrodes capable of pyruvate oxidation which, in the presence of arsenic, wi... | Fuel cells; Arsenic - Detection | 2013-05 |
8 |
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Simonsen, Kyle | Breast cancer knowledge and attitudes among women in Armenia | Background: Breast cancer, the most common invasive cancer among women, has high incidence and mortality rates among women in the Republic of Armenia. Advanced stage at detection limits treatment options and contributes to high morbidity and mortality. Understanding women's breast cancer knowledge a... | Breast - Cancer; Breast - Cancer - Patients - Attitudes; Breast - Cancer - Patients - Armenia (Republic) | 2013-07 |
9 |
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Visser, Joshua | Characterization of G-quadruplexes in DNA repair protein gene sequences and the effects of oxidized guanine lesions on DNA base insertion and elongation | Guanine (G) is one of the four nucleo bases that make up the complex macromolecule deoxyribonucleic acid (DNA). In addition to its ability to Watson-Crick base pair with cytidine (C), guanine can base pair with itself vianon-canonical, Hoogsteen base pairing and form a secondary structure of DNA ca... | DNA repair - Research; G proteins - Pathophysiology - Research; Oxidation, Physiological - Research; Membrane homogenization; Synthetic blood; Artificial oxygen carriers | 2016-05 |
10 |
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Nicolo, Tera | Characterization of mitochondria-modified electrodes | In order to develop an herbicide sensor, yeast, potato, and bovine heart mitochondria were isolated and immobilized onto Toray paper electrodes. Cyclic voltammetry showed two redox peaks at 186 ± 14 mV vs. SCE and -357 ± 24 mV vs. SCE with an E1/2 of -128 mV. Scan rate studies suggested the proces... | Electrodes; Herbicides - Detection | 2013-05 |
11 |
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Odendahl, Nathan | Comparison of popular force fields for molecular modeling of proteins applied to ice binding of the tenebrio molitor antifreeze protein | Ice Binding Proteins (IBPs) are a class of proteins that affect the melting and freezing temperatures of ice. While substantial research has been conducted to understand the properties of IBPs, experimental and molecular dynamics simulations have not satisfactorily explained the mechanism of the i... | Antifreeze proteins - Research; Ice binding proteins; Tenebrio molitor; Antifreeze protein; Force fields | 2016-04 |
12 |
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Besic, Arnel | Creation and characterization of organic mixed conductors | Organic mixed ionic electronic conductors (OMIECs) are conjugated polymers that conduct both ions and electrons. These materials are promising for applications in healthcare and energy technologies, including biosensors and batteries. An obstacle for using these materials in next-generation technolo... | | 2024 |
13 |
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Peterson, Joseph Ryan | Deflagration and detonation modeling of heterogeneous condensed phase explosives | A modeling approach to the deflagration and detonation phenomena is employed to study a variety of explosive scenarios. An engineering model for macroscale reaction of energetic materials over the wide range of explosive reaction from deflagration to detonation is developed based upon solid foundati... | Deflagration phenomena; Detonation phenomena; mesoscale model | 2012-05 |
14 |
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Lim, Koun (Kasha) | Deglycoyslation of glucose oxidase and its application within high power enzymatic fuel cells | To compensate for the increase of carbon dioxide level and the energy exhaust, an enzymatic fuel cell (EFC) has been investigated by researchers. In the paper, a chemical oxidative deglycosylation of an enzyme was investigated to furture improve EFCs. By deglycosylating an enzyme, the distance betwe... | Fuel cells - Research; Electric power - Research; Deglycosylation; Enzymatic fuel cell; Glucose oxidase | 2016-04 |
15 |
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Munn, Jackson | Determining microbial community composition and methane flux or red butte canyon sediment over time | Methane is a potent greenhouse gas that is released from the soil into the atmosphere, which contributes heavily to global warming. One potential way of reducing the amount of methane in the air is through studying methane consuming bacteria (methanotrophs) and how they interact with other microbes ... | | 2022 |
16 |
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Sanders, Sara | Development of a novel, coumarin-europium sensor for reactive oxidizing species | The synthetic framework has been developed for two fluorescent probes of Reactive Oxidizing Species (RoxS) based on a coumarin-europium fluorescence pair. The coumarin moiety's selectivity for hydrogen peroxide coupled with 620 nm shifted emission of the europium will make these novel sensors biolog... | Reactive Oxygen Species - analysis | 2012-05 |
17 |
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Lutz, Kevin | Discovery of platinum (II) cocrystals with highly fluorinated cyanocarbons | This thesis investigates new platinum(II) complex cocrystals with highly fluorinated cyanoaromatics. While π stacking compounds of polycyclic aromatic hydrocarbons and cyanoaromatics have been reported, interactions with transition metal complexes have yet to be explored. Crystal structures for (pp... | | 2023 |
18 |
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Kent, Alexandra | DNA split aptamers as a biosensing platform for the detection of small drug molecules | Prescription drug overdose and abuse is a leading cause of death in the United States. It is a serious issue and has become increasingly problematic as opioids are being prescribed with a higher frequency. For this reason, fast, accurate detection of small drug molecules is crucial. The current stan... | Drug testing; Biosensors; DNA split aptamers | |
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Kim, Alexander H. | DPP Signal Regulation Through O-Linked Glycosylation | Dorsal closure in Drosophila is an embryogenic event that involves coordinated cellular shape changes. A series of interconnected signaling cascades are utilized to accomplish this task, one of which is the Decapentaplegic (Dpp) pathway. Dpp is a member of the TFG-β family of secreted cytokines, wh... | | 2017 |
20 |
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Ballif, Micah | Drugs and Pregnancy: Clinical Management with a Cystic Fibrosis Focus | Despite the large number of women who become pregnant and use a medication during their pregnancy, there is very little information about the safety of the majority of medications. Most drugs approved by the FDA have undetermined teratogenic risk, but their use is prevalent in the management of dise... | | 2019 |
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Gerton, Marina | Effects of carbon sources on secondary metabolite production by teredinibacter turnerae | Shipworms are wood-digesting marine bivalves that rely upon symbiotic bacteria for cellulose digestion. The symbiotic bacteria, which grow intracellularly in shipworm gill tissue, produce cellulases that are then transported to the shipworm's cecum. It has also been hypothesized that the bacteria pr... | | 2023 |
22 |
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Bischoff, Amanda | Elucidating the Mechanism and Predicting the Selectivity of the bis(Pyridine) Silver Permanganate Oxidatiin | The Movassaghi group has recently reported several total syntheses of epipolythiodiketopiperazine derivatives (ETPs), a class of natural products with potent biological activity. A crucial step in their synthesis oxidizes two to four tertiary C-H bonds to form tertiary alcohols using (bis)pyridine s... | | 2016 |
23 |
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Cocke, Rebecca C. | Evaluating the Catalytic Activity of Iron and Nickel Impurities in Bare High-Pressure High-Temperature Nanodiamond | Many metal nanoparticles are used as catalysts for various reactions and are held on supports. High-Pressure High-Temperature nanodiamonds (HPHT ND) are able to support metal nanoparticles even under strenuous chemical environments due to their robust nature. The production of HPHT ND includes the u... | | 2018 |
24 |
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Fernandez, Florence | Evaluation of environmental education in high school science courses across Salt Lake City, Utah | While the effects of pollution become Incredibly more evident in the air of the Salt Lake Valley, many Utah high school students still lack the knowledge and information necessary to take preventative and immediate actions to protect their health and their environment. In this study, the reasons for... | Environmental education -- Utah -- Salt Lake City; Science -- Study and teaching -- Utah -- Salt Lake City; Air -- Pollution -- Utah -- Salt Lake City | 2015-05 |
25 |
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Fan, Huijun | Examination of Y-Deterium isotope effects for the solvolysis of model isoprenoid compounds | Model isoprenoid compounds can undergo two distinct pathways, dissociative or associative nucleophilic substitution depending on the conditions used. The dissociative pathway consists of two steps, involving a carbocation intermediate where the formation of that carbocation is rate determining. The ... | Isopentenoids; Solvolysis; Deuterium - Isotopes | 2012-05 |