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Hawkes, Kristen | Grandmother effects, heterogeneity, and the evolution of human aging: guidance from human-chimpanzee comparisons | In the first paper to present formal theory explaining that senescence is a consequence of natural selection, W. D. Hamilton concluded that human postmenopausal longevity results from the contributions of ancestral grandmothers to the reproduction of their relatives. A grandmother hypothesis, subseq... | Evolution of senescence; Heterogeneity of frailty; Human life history; Menopause; Human aging | 2010-01-01 |
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Hawkes, Kristen | Ovarian follicle loss in humans and mice: lessons from statistical model comparison | Menopause is triggered by the number of ovarian follicles falling below a threshold number and is irreversible because oogonial stem cells disappear after birth. Since it is the result of programmed disappearance of a limited store of follicles, menopause can be predicted using mathematical models b... | Age; Follice; Mathematical; Model; Menopause; Ovary | 2010-01-01 |
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