Honors Theses Open Access
 
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1 Hinchman, Colin4D flow characteristics of left atrial blood flow after atrial fibrillationAtrial fibrillation is the most prevalent cardiac arrhythmia and causes increased risk for stroke, yet accurate pathophysiological diagnosis remains a challenge. This study aimed to further investigate the physiologic biomarkers in the left atrium (LA) related to atrial fibrillation (AF) using 4D fl...2019
2 Hanes, Josh T.A comparison of nuclear thermal rockets with traditional chemical rockets for space transportThe Solar System has multiple destinations that private and governmental space agencies are planning to explore. Missions within the Solar System are both exorbitantly expensive and time intensive projects that involve high risks for the organizations involved. A mission that is currently being...Nuclear rockets - research; space vehicles - design - research; nuclear thermal rockets; chemical rockets; space transport2016-04
3 Lee, Charles Chang SukA demonstration apparatus for optical pumping of rubidiumOptical pumping refers to the use of light in order to elevate ("pump") the spin (intrinsic angular momentum) of an atom or molecule. This process is of interest from a pedagogical and experimental perspective because it encapsulates fundamental properties of atomic physics and quantum mechanics. Fu...Optical pumping -- Research Spin exchange -- Research Rubidium isotopes -- Research2015-05
4 German, MassiellA genetic analysis of VSX2 function in the mouse eyeVsx2 is a homeodomain-containing transcription factor essential for maintenance of neuroretinal identity and neurogenesis. Vsx2 is believed to function via mechanisms that are strictly cell-intrinsic. However, recent research reveals evidence for involvement of Vsx2-mediated cell non-autonomous mech...Neurogenesis - physiology2012-05
5 Sperber, Alexander M.A novel approach to differentiating cardiac fibroblasts from induced pluripotent stem cellsHeart disease remains the leading cause of death in the United States, and such disease is caused by electrical, chemical, or biomechanical imbalances in the heart. The two most abundant cells comprising the heart that are responsible for these functions are cardiomyocytes and cardiac fibroblasts. I...2022
6 Godfrey, RoseA porcine model for the development and testing of preoperative skin preparationsClinical preoperative skin preparations (PSPs) do not eradicate skin flora dwelling in the deepest dermal regions. Survivors constitute a persistent infection risk. In search of solutions, we created a porcine model intended for PSP developmental testing. This model employed microbiological techniqu...2022
7 Martin, IsaacA result concerning the F-Signature and the torsion divisors of strongly F-Regular singularitiesPolstra showed that the cardinality of the torsion subgroup of the divisor class group of a local strongly F-regular ring is finite. In this thesis, we first provide an expository introduction to the field of F-singularities before improving upon Polstra's result by proving that the reciprocal of th...2021
8 Simon, Philip C.A study of the optimized load of a traveling wave thermoacoustic heat engineThermal interaction between differentially heated solid material and ambient gas in a resonator can lead to self-sustained oscillations or the transportation of heat in accordance with the thermoacoustic effect, first explained by Lord Rayleigh. In this research the phenomenon is employed in a lo...Thermoacoustic engine - Research; Energy conservation2016-03
9 Sullivan, Steven M.A trace formula for G2An n-dimensional matrix representation of a group G on a vector space V is a homomorphism from G to GL(V). For our purposes, we consider an irreducible representation to be a representation which cannot be decomposed into the direct sum of smaller-dimensional representations. Let H be a subgroup of ...Trace formulas2013-05
10 Blanton, Joseph P.AC Magnetic Susceptibility of Sub-Millimeter Superconductor Samples at Extreme ConditionsSuperconductivity is a unique state of matter observed at cryogenic temperatures in many materials. Superconductors are defined as materials that have zero DC electrical resistance and perfect diamagnetism below a critical transition temperature, Tc. These properties are very useful for many applica...2018
11 Shapiro, DarienActivation of transient receptor potential ankyrin-1 by wood smoke particulate materialExposure to wood smoke particulate matter (WSPM) has been linked to exacerbation of pre-existing respiratory conditions such as asthma, development of chronic obstructive pulmonary disease (COPD), and premature deaths. While it is clear that WSPM exposure is hazardous to human health, the molecular ...Smoke; Physiological effect2012-05
12 Arave, Rowan A.AKT1 activation promotes the development of melanoma metastasisMetastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT (or protein kinase B) signaling in human melanoma metastases led to the evaluation of the effect of activated AKT1 expression in non-metastatic BRAFV600E/cyclin dependent kinase inhibitor 2a nu...Melanoma; genetics; research; metastasis; genetics; research; biochemistry; genetics2015-12
13 Arnoholt, AlaynaAn analysis on the influence of anxiety in post error slowingAnxiety disorders are among the most common mental disorders and affect 15.7 million Americans each year (Lépine, 2002, p. 4). Anxiety is associated with reduced productivity, physical distress, and other diseases such as depression. Anxiety could also be influential in error response (Compton et a...Americans2021
14 Cummins, HeatherAnalysis of eyes shut (EYS) function during intestinal regeneration in drosophila melanogasterThe intestine is a self-renewing organ under constant stress. It is the first line of defense against toxins and bacteria and enables digestion and nutrient absorption. Its homeostasis (controlled regulation) plays a critical role in the maintenance of organ function and prevention of tumor generati...diseases or cancers; homeostasis; sufficient2019
15 Zhu, JudyAnalysis of the pH-dependent equilibrium relationship between the guanine oxidation products 5-guanidinohydantoin and iminoallantoinOxidation of 2'-deoxyguanosine (dG) results in the major two-electron product 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG) that can undergo further oxidation to other products. One such product is 5-guanidinohydantoin (dGh) that is highly mutagenic and has been found in vivo. The ring architecture of d...Oxidation; guanine oxidation products; 5-guanidinohydantoin; iminoallantoin; equilibrium relationship2015-05
16 Rohaj, AarushiApoptosis efficiency of the transfected elephant and human P35 vectors in P53 varying leiomyosarcoma cellsComparative Oncology is an approach that integrates and connects commonly occurring cancers seen in animals, into studies focused on cancer biology, prevention, and treatment in humans. Studies show that natural mechanisms can suppress cancer 1,000 times more adequately in certain animals than in hu...2021
17 Edwards, Jennifer LynnApplication of a TBHP-mediated Wacker-type oxidation to internal alkenesThe Wacker oxidation allows access to methyl ketones from terminal alkenes. This transformation is important for industrial, synthetic, and medicinal chemists, as carbonyls are present in many natural and pharmaceutical products. With the carbonyl, a wide variety of reactions become available, such ...Wacker-type oxidatioin - Research; TBHP2013-05
18 Pecchia-Bekkum, AnnikaApplications of controlled DNA assembly and disassembly in biosensing and responsive drug deliveryDeoxyribonucleic acid (DNA) provides many exciting functions outside of simply encoding genetic information. Herein, we report two techniques to control the assembly and disassembly of nucleic acids. Within these techniques, DNA is used as a programmable material for biosensing and drug delivery. In...Nucleic acids - Biotechnology2013-08
19 Stahulak, Robert J.Applying Chiral Field Theory to Neutron Star Moments of InertiaIn this work we examine the applications of neutron stars and their unique structure toprovide limits on the range of possible equations of state which describe nuclear matter.We follow the history of developments in nuclear physics and discuss the current state ofknowledge of neutron stars, includ...2019
20 Stahulak, Robert J.Applying chiral field Theory to Neutron Star Moments of InertiaIn this work we examine the applications of neutron stars and their unique structure to provide limits on the range of possible equations of state which describe nuclear matter. We follow the history of developments in nuclear physics and discuss the current state of knowledge of neutron stars, incl...2019
21 Renz, AndyAssessment of exercise-stimulated tissue oxygenation in calf muscle with functional MRIPeripheral artery disease (PAD) affects millions of patients in the USA, and effective diagnosis and management of PAD is a major clinical goal. One promising avenue of research towards the goal is through functional MRI, which provides non-invasive measurement of tissue oxygenation. For a group of ...Arteries - Diseases - Diagnosis; Magnetic resonance imaging - Research; Calf muscle; Peripheral arterial disease; MATLAB2016-04
22 Estrada, JohannaBCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemiaCML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ...Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research2014-04
23 Zhao, MichaelBinary Hermitian Forms and Optimal EmbeddingsLet L=K be a quadratic extension of global fields, and OL the ring of integers of L. We prove two correspondences between (i) binary L-hermitian forms which represent 1 and optimal embeddings of L into a quaternion algebra, (ii) integral binary OL-hermitian forms which represent 1 and embeddings of ...2017
24 Burga, Carlos AlbertoBinary superlattices of semiconductor nanocrystals : a path towards possible high-temperature superconductivityThis thesis provides a platform to experimentally test Dr. Daniel Mattis' theoretical work on the possible superconductive behavior of nanostructured intrinsic semiconductors1-2. The theoretical work hinged on the nano-scale architecture of semiconductors. Therefore, using various types of semicondu...Semiconductor nanocrystals; Superconductivity; Superlattices as materials2013-05
25 Rose, StevenBiofuel cells for self powered arsenic detectionResearch in the Minteer group has centered on procedures for immobilizing enzymes and organelles on carbon electrodes for use in sensory and fuel cell applications. Similar strategies have been used to prepare a series of electrodes capable of pyruvate oxidation which, in the presence of arsenic, wi...Fuel cells; Arsenic - Detection2013-05
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