Honors Theses Open Access
 
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576 Lan, Yung-ChiHYPO-osmolarity and glucose starvation localizes slm1 to mitochondria- A novel stress response pathwaySynthetic Lethal with Mss4 1 (Slm1) is a key protein found in the crossroad of the Membrane Compartment of Can1 (MCC) and the Membrane Compartment of TORC2 (MCT). The two compartments on the plasma membrane of budding yeast (Saccharomyces cerevisiae) are responsible for APC transporter regulation an...2022
577 Weaver, BradleyHypoxia and the mesenchymal transition in gliomaRecent advances in targeted therapy for cancer have had little influence on survival for patients diagnosed with Glioblastoma (GBM, WHO Grade IV tumors), and median survival time remains stagnant at 12-15 months post diagnosis. Genomic profiling of GBM indicates clear phenotypic subsets of these tum...Glioblastoma multiforme; Gliomas; Hypoxia; Mesenchymal transition2014-04
578 Gordon, MatthewHysteresis and the learning-By-doing mechanism in the monetary policy context: a bayesian vector autoregression appoachStandard macroeconomic theory typically assumes that output in the long-run is independent of the short-run business cycle. The hysteresis hypothesis assumes the contrary and supposes that short-run economic shocks can have a permanent effect on the level of output. This paper empirically tests the ...2022
579 Lanier, DeandraI am: the wake of postpostmodernismThe goal of this "essay," a compilation of the genres of fiction, poetry, and literary criticism, is to figure out where contemporary fiction is headed and what postmodernism might be leaving in its wake. This essay is an attempt to push critique through the lens of fiction. It seems that the progre...2011
580 Najarian, Anastasia S.I Choose Life Project : Resolving the Disparity of Political and Human Rights Interventions a Strategic Communication Plan to Implement Treatment for Trauma and Suicide Prevention and Reduce Global Conflict VIA Digital DiplomacyIf one is faced with the daunting challenge of climbing Mount Everest or entering a battlefield, the best option is to follow the lead of someone who has done it before, rather than someone who has only read about it. Such is the case with current trends in addressing human rights interventions for ...2018
581 Fackler, Anderson N.Identification of Kin-20 and UNC-119 Knockout suppressors associated with neuronal development and maintenance in C. elegansNeurons comprise the nervous system-the essential signaling and communication system for nearly all multicellular organisms. To coordinate cells across an entire organism, they must grow to be relatively long. Therefore, neurons extend axons from the cell body. Immature neurons extend growth cones a...2018
582 Johnson, KariAnne RencherIdentification of PASK substrates and/or interacting proteinsPAS kinase (PASK) is an evolutionary conserved serine/threonine kinase that appears to have a role in the regulation of cellular energy metabolism. It has previously been shown that mice lacking PASK (PASK"/_ mice) are resistant to the development of hepatic steatosis (lipid accumulation in the live...Biology2012-05
583 Identification of potential causes for increased central line associated bloostream infection rates in the University of Utah NICUThe University of Utah Newborn Intensive Care Unit (UUNICU) has seen a recent increase in rate of Central Line Associated Bloodstream Infection (CLABSI) after an extended period of 965 days with no CLABSI's. Unfortunately, in the last three years, infection rate has been on average 2.6 CLABSI per ye...2023
584 Varghese, Alyssa A.Identification of virulence factors in invasive haemophilus influenzae isolates causing disease in Utah ChildrenHaemophilus influenzae can cause serious disease in children. After widespread use of the H. influenzae serotype b (Hib) vaccine, H. influenzae serotype a (Hia) became a significant cause of invasive infection in Utah. Although most Utah Hia isolates belong to a sequence type theorized to be less in...2021
585 Black, AlyssaIdentifying hybrid male sterility genes in Drosophila PseudoobscuraSpeciation, the process of one species splitting into two separate species, often involves the evolution of hybrid sterility or hybrid inviability. These reproductive isolating barriers are caused by negative interactions between genes called hybrid incompatibilities. Identifying hybrid incompatibil...Infertility, Male -- Genetic aspects Drosophila pseudoobscura -- Genetics Male sterility genes2015-05
586 Ong, ElaineIdentifying Natural Genetic Modifiers of Apoptosis and Retinal DegenerationApoptosis, or cell death, is an integral part of many diseases such as neurodegeneration, retinal degeneration, and cancer, yet it is unclear how apoptosis varies among individuals in a population. Retinitis pigmentosa (RP) is a retinal degeneration disease characterized by phenotypic heterogeneity ...2018
587 Khuu, ScottIdentifying Retinoic Acid Dependent Mechanisms of Neural Crest Epithelial-Mesenchymal TransitionCancer metastasis is one of the distinguishing traits that make the disease difficult to treat. The steps of tumor invasion are similar to a process called epithelial to mesenchymal transition (EMT). Retinoic acid (RA) is shown to inhibit EMT and may cause an increased transcription of the gene, ski...2017
588 Danielson, HaileyIf i should die before i wakeIn my senior year at the University of Utah, I edited and improved upon the movel I wrote in the Honors Novel Writing Workshop course taught by Michael Gills. My novel If I Should Die Before I Wake is the story of a young woman named Emma meeting a young man named Cale by coincidence, and how they s...2022
589 Wang, WenyiImaging in a homogeneous aluminum plate by using ultrasonic wavesThis project is about detecting and imaging damage (such as cracks) in a plate by using ultrasonic waves. The waves are generated by a source (an ultrasonic transducer) that is part of a robot that can move on the plate. The waves traveling in the plate are recorded at a receiver (another ultrasonic...Ultrasonic transducer - Mathematics; Kirchoff migration - Research2014-12
590 Child, SkyleeImaining an ultimate approach to the healthcare system in the 21st century2023
591 Vyas, YashImmigrants and financial capability in CanadaImmigration has accounted for 65% of Canadian population growth for the past five years, and this percentage is growing. By 2035, immigration is expected to account for nearly all of Canada's net population growth. As the number of immigrants continue to grow, many are beginning to wonder if immigra...2023
592 Kendell, IsaacImmunomodulation improves cancer cell clearance by T cells during multi-antigent T cell hybridizer therapyTreatment of hematopoietic malignancies is challenging due to systemic side effects of current treatments and the possibility of relapse. Multi-antigen T cell hybridizer (MATCH) therapy is a novel treatment system composed of antibody fragments conjugated with morpholino oligonucleotides, which hybr...2024
593 Herman, RyanThe Impact of Dodd-Frank Legislation on the Mortagage Market Risk Environment: A Quantitative and Qualitative ExaminationWithin the last decade, the United States endured what is contemporaneously considered to be the most devastating economic recession since the Great Depression. While a complex array of factors contributed to the downturn, a significant and material contributor was the collapse of the housing market...2018
594 Farese, LudovicaThe impact of Global Health education in American Academic Medical Center (AAMCS)Global health has become an increasingly popular field of study among college and graduate students in the United States. A growing body of literature purports the benefits of Global Health Education (GHEs) in American Academic Medical Centers (AAMCs), including introduction to a wider spectrum of d...2018
595 Larson, JackThe impact of paid family leave on fertility rates in the U.S.This analysis seeks to determine the impact of paid family leave (PFL) laws on fertility rates across the United States, where, unlike in other industrialized nations, no federal mandate exists. The study focuses on the six states that implemented PFL laws prior to 2021 and explores how these polici...2024
596 Foote, CarolThe Impact of Past Drug Enforcement Legislation and Potential Success of a Three-Pronged Approach to the Opioid EpidemicThe opioid epidemic has gained widespread attention over the past decade as overdose and addiction rates soar across the country. Opioid abuse has been a problem for the United States dating back to the Civil War. With the pain revolution and aggressive marketing tactics by prescription drug manufac...2018
597 Au, AlexanderImpact of population density of left atrial remodeling in patients with atrial fibrillationAtrial fibrillation (AF), the most common cardiac arrhythmia and a leading cause of stroke, is characterized by structural changes, or remodeling, in tissues of the left atrium (LA). Late Gadolinium-Enhancement Magnetic Resonance Imaging (LGE-MRI) can noninvasively detect remodeling in the LA, allow...Atrial fibrillation Treatment2012-05
598 Brown, AthenaThe impact of social media on behaviors and attitudes toward television advertsiingSince the year 2000, the average attention span has dropped from 12 seconds to eight seconds (Microsoft, 2015). This weakened ability to focus may be the result of an increased use of social media by today's society. On social media platforms, the content shared is mainly short-form content, meaning...2023
599 Quinn, ChloeThe impact of the Glen Canyon Dam on the Colorado River: options for the futureThe Grand Canyon and the Colorado River at its base are iconic natural features of the western United States that are revered by many. This landscape may be well known for its resplendent red canyon walls and beautiful river with huge whitewater, but it is also famous for the monstrous dams that con...2023
600 Woolston, Caleb M.Impact of trauma exposure and posttraumatic stress symptoms on baseline self-reported safety behaviors versus observer-rated safety behaviors during the trauma film paradigmBackground: Post-traumatic stress disorder (PTSD) is a high burden disorder marked by safety behaviors (SB), which are covert or overt actions used to escape distressing feelings or places. However, literature suggests scores on observer-rated and self-reported SBs can be discrepant, creating a need...2022
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