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Creator | Title | Description | Subject | Date |
| 551 |
 |
Davidson, Diane W. | Species diversity and community organization in desert seed-eating ants | Patterns of species diversity and community organization in desert seed-eating ants were studied in 10 habitats on a longitudinal gradient of increasing rainfall extending from southeastern California, through southern Arizona, and into southwestern New Mexico. Local communities of harvester ants... | Ants; Arizona; California; Communities; Competition; Desert Granivores; Diversity; Insects; New Mexico; Novomessor; Pheidole; Pogonomyrmex; Resource allocation; Veromessor. | 1977 |
| 552 |
 |
Adler, Frederick R. | Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis | Lung function, acute pulmonary exacerbations (APE), and weight are the best clinical predictors of survival in cystic fibrosis (CF); however, underlying mechanisms are incompletely understood. Biomarkers of current disease state predictive of future outcomes might identify mechanisms and provide tre... | | 2012-01-01 |
| 553 |
 |
Ehleringer, James R.; Rickart, Eric Allan; Dearing, Maria-Denise | Stable isotope ratios (?15N AND ?13C) of syntopic shrews (SOREX) | Local species richness in shrew (Soricidae) assemblages is often high, and the mechanisms of ecological separation remain relatively unexplored. In this study, hair samples from 6 species of Sorex in 3 separate assemblages were analyzed for stable carbon (13C/12C) and nitrogen (15N/14N) isotope rati... | | 2004 |
| 554 |
 |
Olivera, Baldomero M. | Stapling mimics noncovalent interactions of γ-carboxyglutamates in conantokins, peptidic antagonists of N-methyl-D-aspartic acid receptors | Background: Can dicarba bridges (stapling) replace noncovalent interactions that stabilize helical conformation of neuroactivepeptides? Results: A rational design, synthesis, structural, and functional characterization of stapled conG analogs that target NMDAreceptors is reported. Conclusion: Staple... | | 2012-01-01 |
| 555 |
 |
Adler, Frederick R. | Stochasticity, complex spatial structure, and the feasibility of the shifting balance theory | Sewall Wright's shifting balance theory of evolution posits a mechanism by which a structured population may escape local fitness optima and find a global optimum. We examine a one-locus, two-allele model of underdominance in populations with differing spatial arrangements of demes, both analyticall... | Fitness landscape; Sewall Wright; Underdominance | 2006 |
| 556 |
 |
Olivera, Baldomero M.; Yoshikami, Doju; Bulaj, Grzegorz | Structural basis for tetrodotoxin-resistant sodium channel binding by μ-conotoxin SmIIIA | SmIIIA is a new μ-conotoxin isolated recently from Conus stercusmuscarum. Although it shares several biochemical characteristics with other μ-conotoxins (the arrangement of cysteine residues and a conserved arginine believed to interact with residues near the channel pore), it has several distin... | Conotoxins; Conotoxin SmIIIA; Tetrodotoxin | 2003 |
| 557 |
 |
Olivera, Baldomero M.; Bulaj, Grzegorz | Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif | Conotoxin gm9a, a putative 27-residue polypeptide encoded by Conus gloriamaris, was recently identified as a homologue of the "spasmodic peptide", tx9a, isolated from the venom of the mollusk-hunting cone shell Conus textile (Lirazan, M. B., Hooper, D., Corpuz, G. P., Ramilo, C. A., Bandyopadhyay... | Conotoxins; P-superfamily spasmodic conotoxin; Cystine knot motif | 2002 |
| 558 |
 |
Olivera, Baldomero M.; Zhang, MinMin; Azam, Layla; Yoshikami, Doju; Bulaj, Grzegorz | Structure/function characterization of μ-Conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels | Peptide neurotoxins from cone snails continue to supply compounds with therapeutic potential. Although several analgesic conotoxins have already reached human clinical trials, a continuing need exists for the discovery and development of novel nonopioid analgesics, such as subtype-selective sodium c... | Conotoxins; 956;-Conotoxin KIIIA; Neuronal blocker; Neurotoxins; Sodium channel blockers | 2007 |
| 559 |
 |
Ehleringer, James R. | Study of ecosystems in the context of global change | Global change research requires not only knowledge of how individual species (e.g. pests) respond to climate and land-use change, but also an understanding of the responses of whole systems to their multiple and interacting drivers. An upscaling from single systems to landscapes and continents is an... | Ecosystems; Global change | 1999 |
| 560 |
 |
Adler, Frederick R. | Stumped by trees? A generalized null model for patterns of organismal diversity | Evolutionary biologists increasingly have become interested in the factors determining the structure of phylogenetic trees. For example, highly asymmetric trees seem to suggest that the probability of extinction and/or speciation differs among lineages. | Evolutionary diversification; phylogenetic topologies; speciation | 1995 |
| 561 |
 |
Olivera, Baldomero M. | Subfamily Turrinae in the Philippines: the genus Turris (Roding, 1798) | Marine gastropods of the family Turridae, commonly known as turrids, comprise the largest living group of venomous snails. The taxonomy of this group, however, has been generally neglected. In this work, the genus Tunis (Roding 1798) is discussed. Out of more than 200 different turrid genera, this g... | | 1999-01-01 |
| 562 |
 |
Adler, Frederick R. | Super- and coinfection: filling the range | How many different strains of a disease can coexist in a single population of hosts? What effect do different mechanisms of coexistence have on the properties of diseases? The principle of competitive exclusion (Armstrong and McGehee 1980; Levin 1970) states that no more species can coexist in a sys... | Superinfection; Virulence; Coexistence | 2002 |
| 563 |
 |
Goller, Franz | Superfast vocal muscles control song production in songbirds | Birdsong is a widely used model for vocal learning and human speech, which exhibits high temporal and acoustic diversity. Rapid acoustic modulations are thought to arise from the vocal organ, the syrinx, by passive interactions between the two independent sound generators or intrinsic nonlinear dyna... | Vocal muscles; Syringeal muscles; Sturnus vulgaris | 2008 |
| 564 |
 |
Beckerle, Mary C.; Hoffman, Laura M. | Supervillin modulation of focal adhesions involving TRIP6/ZRP-1 | Cell-substrate contacts, called focal adhesions (FAs), are dynamic in rapidly moving cells. We show that supervillin (SV)-a peripheral membrane protein that binds myosin II and F-actin in such cells-negatively regulates stress fibers, FAs, and cell-substrate adhesion. The major FA regulatory sequenc... | Supervillin; Focal adhesions; Zyxin; LIM domains; TRIP6 | 2006 |
| 565 |
 |
Potts, Wayne K. | Surprisingly uneven distribution of the T cell receptor Vβ repertoire in wild mice | Heterodimeric TCRa/Bs are made up of combinations of V D, J, and C elements. The majority of laboratory inbred mouse strains are of the VBh haplotype and have at least 20 VB genes from which to construct TCRs (1, 2); however, a number of strains have been reported to have deletions of large portion... | | 1990 |
| 566 |
 |
Capecchi, Mario R.; Thomas, Kirk R. | Swaying is a mutant allele of the proto-oncogene Wnt-1 | Mice homozygous for the recessive mutation swaying (SW) are characterized by ataxia and hypertonia, attributed to the malformation of anterior regions of the cerebellum. We show that SW is a deletion of a single base pair from the proto-oncogene Wnf-1. The deletion is predicted to cause premature t... | Swaying allele; protooncogene Wnt-1; Mutant genes; Mutant alleles | 1991 |
| 567 |
 |
Clayton, Dale H. | Swiftlets on islands: genetics and phylogeny of the Seychelles and Mascarene swiftlets | Populations on islands are isolated from mainland populations and are thus expected to diverge and speciate from mainland relatives. We investigated die phylogenetic position and taxonomic rank of the Seychelles and Mascarene swiftlets using nuclear (fibrinogen intron 7) and mitochondrial (cytochr... | Aerodramus Francicus; Aerodramus elaphrus; Collocalia; Apodidae; Cytochrome b; Fibrinogen intron 7; Echolocation; Seychelles; Mascarene Islands | 1999 |
| 568 |
 |
Capecchi, Mario R. | Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. | We have used site-specific mutagenesis to change the anticodon of a Xenopus laevis tyrosine tRNA gene so that it would recognize ochre codons. This tRNA gene is expressed when amplified in monkey cells as part of a SV40 recombinant and efficiently suppresses termination at both the ochre codon separ... | Xenopus; Nucleic Acid Conformation; Kidney; DNA Restriction Enzymes | 1984-11 |
| 569 |
 |
Goller, Franz | Synthesizing bird song | In this work we present an electronic syrinx: an analogical integrator of the equations describing a model for sound production by oscine birds. The model depends on time varying parameters with clear biological interpretation: the air sac pressure and the tension of ventral syringeal muscles. We te... | Syrinx; Tension; Transducer | 2005 |
| 570 |
 |
Bohs, Lynn A. | Systematics of Solanum section Allophyllum (Solanaceae) | Three species of Solarium are included in a new section, Solarium sect. Allophyllum. Two of the species, S. allophyllum and S. mapiriense, have been previously known; the third, S. morellifolium Bohs, is described as new. The combination of characters exhibited by members of this section, such as un... | Solanum section Allophyllum; Solanum allophyllum; Solanum morellifolium; Solanum mapiriense | 1990 |
| 571 |
 |
Olivera, Baldomero M. | T-superfamily of conotoxins | We report the discovery and initial characterization of the T-superfamily of conotoxins. Eight different T-superfamily peptides from five Conus species were identified; they share a consensus signal sequence, and a conserved arrangement of cysteine residues (- -CC- -CC-). T-superfamily peptides... | Conotoxins; T-superfamily | 1999 |
| 572 |
 |
Capecchi, Mario R. | Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. | Implantation within the mammalian uterus elicits dramatic changes in the growth, differentiation, and morphogenesis of the conceptus. This process is interrupted in mice carrying a targeted disruption of the murine evx1 gene, a homolog of the Drosophila even-skipped (eve) gene. Upon implantation, pr... | Extraembryonic; Homozygotes; Drosophila | 1994-08-15 |
| 573 |
 |
Thomas, Kirk R.; Capecchi, Mario R. | Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. | The int-1 proto-oncogene was first identified as a gene activated in virally induced mouse mammary tumours. Expression studies, however, suggest that the normal function of this gene may be in spermatogenesis and in the development of the central nervous system. Genes sharing sequence similarity wit... | Animals; Blastocyst; Cell Line; Chimera; DNA; Female; Genotype; Heterozygote; Homozygote; Male; Mice, Inbred C57BL; Motor Activity | 1990-08-30 |
| 574 |
 |
Beckerle, Mary C.; Hoffman, Laura M. | Targeted disruption of the murine zyxin gene | Zyxin is an evolutionarily conserved protein that is concentrated at sites of cell adhesion, where it associates with members of the Enabled (Ena)/vasodilator-stimulated phosphoprotein (VASP) family of cytoskeletal regulators and is postulated to play a role in cytoskeletal dynamics and signaling. | Zyxin | 2003 |
| 575 |
 |
Olivera, Baldomero M. | Targeted mutagenesis by homologous recombination in D. melanogaster | We used a recently developed method to produce mutant alleles of five endogenous Drosophila genes, including the homolog of the p53 tumor suppressor. Transgenic expression of the FLP site-specific recombinase and the I-SceI endonuclease generates extrachromosomal linear DNA molecules in vivo. Thes... | | 2002 |
