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1 Couldwell, William T.Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitroDirect measurement of protein kinase C (PKC) activity in vitro revealed a significant increase in the activity of the enzyme in all human malignant glioma lines examined and the rat C6 tumor in comparison with control nonneoplastic astrocyte and mixed glial cultures. The total and particulate PKC ac...Brain neoplasms; Flow cytometry; Glioma; Phorbol ester; Protein kinase C1991
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