Neutrophilic myelocyte

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Title Neutrophilic myelocyte
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2007-12-01
Subject Blood; Bone Marrow; Electron microscopy; Neutrophilic myelocyte; Neutrophilic granulocyte; Primary granule; Secondary granule; Azurophilic granule; Lysosome
Description Scheme electron microscopy. From CFU-S (colony forming units-spleen) stem cells arise CFU-GM (colony forming unit-granulocyte/monocyte) stem cells. The latter divide by mitoses and differentiate via promyeloblasts and myeloblasts into myelocytes (the last proliferative stage). The neutrophilic myelocyte (10-15 μm) contains a large nucleus (nucleoli disappear) and well developed organelles, a distinct Golgi area and specific or secondary granules. The primary ('non-specific' or azurophilic) granules (0.3-0.4 μm) are electron-grey (1) and contain among others acid phosphatase and arylsulfatase. The secondary (specific) electron-dense granules (2) contain lysosome and phagocytin.
Subtype Image
Format image/jpeg
Rights http://creativecommons.org/licenses/by-nc-nd/3.0/
Collection Poja Histology Collection - Blood & Bone Marrow Subset
ARK ark:/87278/s6h44trv
Setname ehsl_heal
ID 891049
Reference URL https://collections.lib.utah.edu/ark:/87278/s6h44trv
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