Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis

http://www.cs.unc.edu/Research/MIDAG/pubs/papers/MICCAI05_Corouge_DT.pdf
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Links to Media http://www.cs.unc.edu/Research/MIDAG/pubs/papers/MICCAI05_Corouge_DT.pdf
Publication Type journal article
Creator Gerig, Guido
Other Author Corouge, Isabelle; Fletcher, P. Thomas; Joshi, Sarang; Gouttard, Sylvain
Title Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis
Date 2006-01-01
Description Diffusion tensor imaging (DTI) has become the major modality to study properties of white matter and the geometry of fiber tracts of the human brain. Clinical studies mostly focus on regional statistics of fractional anisotropy (FA) and mean diffusivity (MD) derived from tensors. Existing analysis techniques do not sufficiently take into account that the measurements are tensors, and thus require proper interpolation and statistics based on tensors, and that regions of interest are fiber tracts with complex spatial geometry. We propose a new framework for quantitative tract-oriented DTI analysis that includes tensor interpolation and averaging, using nonlinear Riemannian symmetric space. As a result, tracts of interest are represented by the geometry of the medial spine attributed with tensor statistics calculated within cross-sections. Examples from a clinical neuroimaging study of the early developing brain illustrate the potential of this new method to assess white matter fiber maturation and integrity.
Type InteractiveResource
Publisher Elsevier
Journal Title Medical Image Analysis
Volume 10
Issue 5
First Page 786
Last Page 798
DOI 10.1016/j.media.2006.07.003
Subject Diffusion tensor interpolation, Diffusion tensor statistics, DTI analysis, Fiber tract modeling
Language eng
Bibliographic Citation Corouge, I., Fletcher, P. T., Joshi, S., Gouttard, S., & Gerig, G. (2006). Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis. Medical Image Analysis, 10(5), 786-98.
Rights Management (c) Elsevier ; Authors manuscript from Corouge, I., Fletcher, P. T., Joshi, S., Gouttard, S., & Gerig, G. (2006). Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis. Medical Image Analysis, 10(5), 786-98. http://dx.doi.org/10.1016/j.media.2006.07.003.
Format Medium application/html
Identifier uspace, 19269
ARK ark:/87278/s6q278cm
Setname ir_uspace
Date Created 2015-04-01
Date Modified 2021-05-06
ID 712907
Reference URL https://collections.lib.utah.edu/ark:/87278/s6q278cm
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