Probabilistic white matter fiber tracking using, particle filtering and von mises-fisher sampling

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771420/
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Links to Media http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771420/
Publication Type journal article
Creator Gerig, Guido
Other Author Zhang, Fan; Hancock, Edwin R.; Goodlett, Casey
Title Probabilistic white matter fiber tracking using, particle filtering and von mises-fisher sampling
Date 2009-01-01
Description Standard particle filtering technique have previously been applied to the problem of fiber tracking by Brun et al. (2002) and Bjornemo et al. (2002). However, these previous attempts have not utilised the full power of the technique, and as a result the fiber paths were tracked in a goal directed way. In this paper we provide an advanced technique by presenting a fast and novel probabilistic method for white matter fiber tracking in diffusion weighted MRI (DWI), which takes advantage of the weighting and resampling mechanism of particle filtering. We formulate fiber tracking using a nonlinear state space model which captures both smoothness regularity of the fibers and the uncertainties in the local fiber orientations due to noise and partial volume effects. Global fiber tracking is then posed as a problem of particle filtering. To model the posterior distribution, we classify voxels of the white matter as either prolate or oblate tensors. We then construct the orientation distributions for prolate and oblate tensors separately. Finally, the importance density function for particle filtering is modeled using the von Mises-Fisher distribution on a unit sphere. Fast and efficient sampling is achieved using Ulrich-Wood's simulation algorithm. Given a seed point, the method is able to rapidly locate the globally optimal fiber and also provides a probability map for potential connections. The proposed method is validated and compared to alternative methods both on synthetic data and real-world brain MRI datasets.
Type InteractiveResource
Publisher Elsevier
Journal Title Medical Image Analysis
Volume 13
Issue 1
First Page 5
Last Page 18
DOI doi.org/10.1016/j.media.2008.05.001
Subject Diffusion tensor MRI; Tractography; Probabilistic fiber tracking; Particle filtering; von Mises-Fisher sampling
Language eng
Bibliographic Citation Zhang, F., Hancock, E. R., Goodlett, C., & Gerig, G. (2009). Probabilistic white matter fiber tracking using, particle filtering and von mises-fisher sampling. Medical Image Analysis, 13(1), 5-18.
Rights Management (c) Elsevier ; Authors manuscript from Zhang, F., Hancock, E. R., Goodlett, C., & Gerig, G. (2009). Probabilistic white matter fiber tracking using, particle filtering and von mises-fisher sampling. Medical Image Analysis, 13(1), 5-18. http://dx.doi.org/10.1016/j.media.2008.05.001.
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Identifier uspace, 19229
ARK ark:/87278/s6nc99bt
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Date Created 2015-03-09
Date Modified 2015-03-09
ID 712861
Reference URL https://collections.lib.utah.edu/ark:/87278/s6nc99bt