Group statistics of DTI fiber bundles using spatial functions of tensor measures

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Publication Type pre-print
School or College <blank>
Department <blank>
Creator Gerig, Guido
Other Author Goodlett, Casey B.; Fletcher, P. Thomas; Gilmore, John H.
Title Group statistics of DTI fiber bundles using spatial functions of tensor measures
Date 2008-01-01
Description We present a framework for hypothesis testing of differences between groups of DTI ber tracts. An anatomical, tract-oriented coordinate system provides a basis for estimating the distribution of diffusion properties. The parametrization of sampled, smooth functions is normalized across a population using DTI atlas building. Functional data analysis, an extension of multivariate statistics to continuous functions is applied to the problem of hypothesis testing and discrimination. B-spline models of fractional anisotropy (FA) and Frobenius norm measures are analyzed jointly. Plots of the discrimination direction provide a clinical interpretation of the group differences. The methodology is tested on a pediatric study of subjects aged one and two years.
Type Text
Publisher Springer
Volume 5241
First Page 1068
Last Page 1075
Language eng
Bibliographic Citation Goodlett, C., Fletcher, P. T., Gilmore, J., & Gerig, G. (2008). Group statistics of DTI fiber bundles using spatial functions of tensor measures. Proceedings of Medical Image Computing and Computer Assisted Intervention 2008, Lecture Notes in Computer Science LNCS, 5241, 1068-75.
Rights Management (c) Springer (The original publication is available at www.springerlink.com) The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-540-85988-8_127.
Format Medium application/pdf
Format Extent 1,352,262 bytes
Identifier uspace,19232
ARK ark:/87278/s6jm5ksx
Setname ir_uspace
Date Created 2015-03-06
Date Modified 2015-03-06
ID 712854
Reference URL https://collections.lib.utah.edu/ark:/87278/s6jm5ksx
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