Diffusion tensor imaging: application to the study of the developing brain

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Publication Type pre-print
School or College <blank>
Department <blank>
Creator Gerig, Guido
Other Author Cascio, Carissa J.; Piven, Joseph
Title Diffusion tensor imaging: application to the study of the developing brain
Date 2007-01-01
Description Objective: To provide an overview of diffusion tensor imaging (DTI) and its application to the study of white matter in the developing brain, in both healthy and clinical samples. Method: The development of DTI and its application to brain imaging of white matter tracts is discussed. 48 studies using DTI to examine diffusion properties of the developing brain are reviewed in the context of the structural magnetic resonance imaging (MRI) literature. Reports of how brain diffusion properties are affected in pediatric clinical samples and how they relate to cognitive and behavioral phenotypes are reviewed. Results: DTI has been successfully used to describe white matter development in pediatric samples. Changes in white matter diffusion properties are consistent across studies, with anisotropy increasing and overall diffusion decreasing with age. Diffusion measures in relevant white matter regions correlate with behavioral measures in healthy children and in clinical pediatric samples. Conclusions: DTI is an important tool for providing a more detailed picture of developing white matter than can be obtained with conventional MRI alone. Keywords: brain, development, white matter, diffusion tensor imaging, magnetic resonance imaging.
Type Text
Publisher Elsevier
Volume 46
Issue 2
First Page 213
Last Page 223
Language eng
Bibliographic Citation Cascio, C. J., Gerig, G., & Piven, J. (2007). Diffusion tensor imaging: application to the study of the developing brain. Journal of the American Academy of Child & Adolescent Psychiatry, 46(2), 213-23.
Rights Management (c) Elsevier ; Authors manuscript from Cascio, C. J., Gerig, G., & Piven, J. (2007). Diffusion tensor imaging: application to the study of the developing brain. Journal of the American Academy of Child & Adolescent Psychiatry, 46(2), 213-23. http://dx.doi.org/10.1097/01.chi.0000246064.93200.e8.
Format Medium application/pdf
Format Extent 2,409,719 bytes
Identifier uspace,19242
ARK ark:/87278/s6xw7tz0
Setname ir_uspace
Date Created 2015-03-06
Date Modified 2015-03-06
ID 712851
Reference URL https://collections.lib.utah.edu/ark:/87278/s6xw7tz0
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