Tumor-induced structural radiometric asymmetry in brain images

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Publication Type pre-print
School or College <blank>
Department <blank>
Creator Gerig, Guido
Other Author Lorenzen, Peter; Joshi, Sarang; Bullitt, Elizabeth
Title Tumor-induced structural radiometric asymmetry in brain images
Date 2001-01-01
Description This paper presents a general framework for analyzing structural and radiometric asymmetry in brain images. In a healthy brain, the left and right hemispheres are largely symmetric across the mid-sagittal plane. Brain tumors may belong to one or both of the following categories: mass-effect, in which the diseased tissue displaces healthy tissue; and infiltrating, in which healthy tissue has become dis structural asymmetry by displacing healthy tissue, and may cause radiometric asymmetry in adjacent normal structures due to edema. Infiltrating tumors have a different radiometric response from healthy tissue. Thus, structural and radiometric asymmetries across the mid-sagittal plane in bruin images provide important cues that tumors may be present. We have developed a framework that registers images with their reflections across the mid-sagittal plane. The registration process accounts for tissue displacement through large deformation image warping. Radiometric differences are taken into account through an additive intensity field. We present an efficient multi-scale algorithm for the joint estimation of structural and radiometric asymmetry.
Type Text
Publisher Institute of Electrical and Electronics Engineers (IEEE)
First Page 163
Last Page 170
Language eng
Bibliographic Citation Lorenzen, P., Joshi, S., Gerig, G., & Bullitt, E. (2001). Tumor-induced structural radiometric asymmetry in brain images. Workshop on Mathematical Methods in Biomedical Image Analysis (MMBIA), 163-70.
Rights Management (c) 2001 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Format Medium application/pdf
Format Extent 695,654 bytes
Identifier uspace,19300
ARK ark:/87278/s6sb7fvb
Setname ir_uspace
Date Created 2015-02-20
Date Modified 2015-02-24
ID 712829
Reference URL https://collections.lib.utah.edu/ark:/87278/s6sb7fvb
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