Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart Study

Update item information
Publication Type pre-print
School or College School of Medicine
Department Internal Medicine
Creator Hunt, Steven C.
Other Author Robbins, Jeremy M.; Petrone, Andrew B.; Ellison, R. Curtis; Carr, J. Jeffrey ; Heiss, Gerardo; Arnett, Donna K.; Gaziano, J. Michael; Djoussé, Luc
Title Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart Study
Date 2014-01-01
Description Background and Aims: Eggs are a ubiquitous and important source of dietary cholesterol and nutrients, yet their relationship to coronary heart disease (CHD) remains unclear. While some data have suggested a positive association between egg consumption and CHD, especially among diabetic subjects, limited data exist on the influence of egg consumption on subclinical disease. Thus, we sought to examine whether egg consumption is associated with calcified atherosclerotic plaques in the coronary arteries. Methods: In a cross-sectional design, we studied 1848 participants of the NHLBI Family Heart Study without known CHD. Egg consumption was assessed by a semi-quantitative food frequency questionnaire and coronary-artery calcium (CAC) was measured by cardiac CT. We defined prevalent CAC using an Agatston score of at least 100 and fitted generalized estimating equations to calculate prevalence odds ratios of CAC. Results: Mean age was 56.5 years and 41% were male. Median consumption of eggs was 1/week. There was no association between frequency of egg consumption and prevalent CAC. Odds ratios (95% CI) for CAC were 1.0 (reference), 0.95 (0.66-1.38), 0.94 (0.63-1.40), and 0.90 (0.57-1.42) for egg consumption of almost never, 1-3 times per month, once per week, and 2+ times per week, respectively (p for trend 0.66), adjusting for age, sex, BMI, smoking, alcohol, physical activity, income, field center, total calories, and bacon.
Type Text
Publisher Elsevier
Volume 9
Issue 3
First Page e131
Last Page e135
Language eng
Bibliographic Citation Robbins, J. M., Petrone, A. B., Ellison, R. C., Hunt, S. C., Carr, J. J., Heiss, G., Arnett, D. K., Gaziano, J. M., & Djoussé, L. (2014). Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart Study. e-SPEN Journal, 9(3), e131-5.
Rights Management (c) Elsevier ; Authors manuscript from Robbins, J. M., Petrone, A. B., Ellison, R. C., Hunt, S. C., Carr, J. J., Heiss, G., Arnett, D. K., Gaziano, J. M., & Djouss√©, L. (2014). Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart Study. e-SPEN Journal, 9(3), e131-5. http://dx.doi.org/10.1016/j.clnme.2014.04.004
Format Medium application/pdf
Format Extent 1,335,763 bytes
Identifier uspace,18690
ARK ark:/87278/s6ns441z
Setname ir_uspace
Date Created 2014-06-30
Date Modified 2014-06-30
ID 712588
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ns441z
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