Criterion-based screening for sexually transmitted infection: sensitivity, specificity, and predictive values of commonly used questions

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Publication Type pre-print
School or College College of Nursing
Department Nursing College of
Creator Murphy, Patricia A.
Other Author Jacobson, Janet; Turok, David K.
Title Criterion-based screening for sexually transmitted infection: sensitivity, specificity, and predictive values of commonly used questions
Date 2012-01-01
Description Background: Practice protocols that mandate pre-screening for sexually transmitted infection prior to insertion of an intrauterine device for contraception can pose obstacles for women seeking this highly effective method of birth control. Some practices screen for presumed risk factors for sexually transmitted infection in order to identify those who may be infected, or those in whom laboratory testing should be obtained. The value of such criterion-based screening is unclear. Design: Data from a prospective observational trial of offering the copper intrauterine device for emergency contraception were used to assess the value of several screening questions in predicting the presence of sexually transmitted infection. Criteria evaluated were age under 25, history of a sexually transmitted infection, and having 2 or more sexual partners in the previous 3 months. The sensitivity, specificity, and likelihood ratio of both positive and negative tests, and positive and negative predictive values were calculated for three separate questions, as well as for combinations of these three questions. Results: There were 197 women who received a copper intrauterine device for emergency contraception at the same time they were tested for sexually transmitted infection. In this sample, there were 8 cases of Chlamydia trachomatis identified, and no cases of Neisseria gonorrhea. The sensitivity of individual and combined questions in identifying those who were infected ranged from 0 to 88%; specificity ranged from 37-97%. The positive predictive values for single or combined screening questions were in the range of 4-6%. Likelihood ratios for both positive and negative tests did not change post-test likelihood of disease in any appreciable way.
Type Text
Publisher Wiley-Blackwell
Volume 57
Issue 6
First Page 622
Last Page 628
Language eng
Bibliographic Citation Murphy, P. A., Jacobson, J., & Turok, D. K. (2012). Criterion-based screening for sexually transmitted infection: sensitivity, specificity, and predictive values of commonly used questions. Journal of Midwifery and Womens Health, 57(6), 622-8.
Rights Management (c) Wiley-Blackwell The definitive version is available at www3.interscience.wiley.com
Format Medium application/pdf
Format Extent 1,147,164 bytes
Identifier uspace,18143
ARK ark:/87278/s6bg5z4q
Setname ir_uspace
Date Created 2014-05-30
Date Modified 2014-06-03
ID 712575
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bg5z4q
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