Resistance exercise with older fallers: Its impact on intermuscular adipose tissue

Update item information
Publication Type pre-print
School or College School of Medicine
Department Physical Therapy
Creator LaStayo, Paul C.
Other Author Jacobs, Janelle L.; Marcus, Robin L.; Morrell, Glen
Title Resistance exercise with older fallers: Its impact on intermuscular adipose tissue
Date 2014-01-01
Description Objective. Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditional resistance training. Methods. Seventy-seven older adults (age 75.5 ± 6.8) with multiple comorbidities and a history of falling completed a three-month exercise intervention paired with either eccentric or traditional resistance training. MRI of the mid-thigh was examined at three time points to determine changes in muscle composition after intervention. Results. No differences in IMAT were observed over time, and there were no differences in IMAT response between intervention groups. Participants in the traditional group lost a significant amount of lean tissue (𝑃 = 0.007) in the nine months after intervention,while participants in the eccentric group did not (𝑃 = 0.32). When IMAT levels were partitioned into high and low IMAT groups, there were differential IMAT responses to intervention with the high group lowering thigh IMAT. Conclusions.There is no decrease in thigh IMAT after a three-month exercise intervention in older adults at risk for falling and no benefit to eccentric training over traditional resistance training for reducing IMAT in these individuals.
Type Text
Publisher Hindawi Publishing Corporation
Volume 2014
First Page 1
Last Page 7
Language eng
Bibliographic Citation Jacobs, J. L., Marcus, R. L., Morrell, G., & Lastayo, P. (2014). Resistance exercise with older fallers: Its impact on intermuscular adipose tissue. BioMed Research International, 2014, 398960, 1-7.
Rights Management (c) LaStayo, Paul C. http://creativecommons.org/licenses/by/3.0/legalcode
Format Medium application/pdf
Format Extent 1,265,734 bytes
Identifier uspace,18689
ARK ark:/87278/s6351vg5
Setname ir_uspace
Date Created 2014-05-19
Date Modified 2014-05-20
ID 712546
Reference URL https://collections.lib.utah.edu/ark:/87278/s6351vg5
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