Interictal infraslow activity in patients with epilepsy

Update item information
Publication Type pre-print
School or College School of Medicine
Department Neurology
Creator Rodin, Ernst A.
Other Author Constantino, T.; Bigelow, J.
Title Interictal infraslow activity in patients with epilepsy
Date 2014-01-01
Description Objective: To evaluate if interictal infraslow activity (ISA), as obtained from a conventional EEG system, can contribute information about the epileptogenic process. Methods: The entire long-term intracranial monitoring sessions of 12 consecutive patients were evaluated on an XLTEK system for ISA. Three additional patients had long-term scalp recordings. Results: In intracranial as well as scalp recordings, the ISA background was consistently higher in the waking state than during sleep. From this background emerged intermittently focal changes, which could achieve in intracranial recordings millivolt amplitudes, while they remained in the microvolt range in scalp recordings. Although they were mainly contiguous between adjacent channels, this was not necessarily the case and intermittent build-up could be seen distant from the epileptogenic zone or radio-graphic lesion. Conclusions: Interictal ISA can be detected in routine intracranial and scalp recordings, without the need for DC amplifiers, and can provide additional information. Significance: Since ISA is a separate element of the electromagnetic spectrum, apparently non-neuronal in origin, its assessment should be included not only in the pre-surgical evaluation of epilepsy patients but also in patients with other neurologic disorders and normal volunteers.
Type Text
Publisher Elsevier
Volume 125
Issue 5
First Page 919
Last Page 929
Language eng
Bibliographic Citation Rodin, E., Constantino, T., & Bigelow, J. (2014). Interictal infraslow activity in patients with epilepsy. Clinical Neurophysiology, 125(5), 919-29.
Rights Management (c) Elsevier ; Authors manuscript from Rodin, E., Constantino, T., & Bigelow, J. (2014). Interictal infraslow activity in patients with epilepsy. Clinical Neurophysiology, 125(5), 919-29. http://dx.doi.org/10.1016/j.clinph.2013.10.014
Format Medium application/pdf
Format Extent 8,096,472 bytes
Identifier uspace,18629
ARK ark:/87278/s66x2m54
Setname ir_uspace
Date Created 2014-05-19
Date Modified 2014-05-20
ID 712545
Reference URL https://collections.lib.utah.edu/ark:/87278/s66x2m54
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