Case-control study of risk factors for spasmodic dysphonia: a comparison with other voice disorders

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Publication Type pre-print
School or College College of Health
Department Communication Sciences & Disorders
Creator Roy, Nelson
Other Author Tanner, Kristine; Merrill, Ray M.; Sauder, Cara; Houtz, Daniel R.; Smith, Marshall E.
Title Case-control study of risk factors for spasmodic dysphonia: a comparison with other voice disorders
Date 2012-01-01
Description Objectives: This epidemiology study examined risk factors uniquely associated with spasmodic dysphonia (SD). Study Design: Case-control. Methods: A questionnaire was administered to 150 patients with SD (with and without coexisting vocal tremor) and 136 patients with other structural, neurological, and functional voice disorders (excluding SD and vocal tremor). Questions included personal and family medical histories, environmental exposures, trauma, illnesses, voice use habits and the Short Form 36. Results: Several factors were uniquely associated with SD (α=0.05), including: (1) a personal history of cervical dystonia, sinus and throat illnesses, mumps, rubella, dust exposure and frequent volunteer voice use, (2) a family history of voice disorders, (3) an immediate family history of vocal tremor and meningitis, and (4) an extended family history of head and neck tremor, ocular disease, and meningitis. Vocal tremor coexisted with SD in 29% of cases. Measles and mumps vaccines were protective for SD. Conclusions: SD is likely multi-factorial, associated with several endogenous and exogenous factors. Certain viral exposures, voice use patterns, and familial neurological conditions may contribute to the onset of SD later in life.
Type Text
Publisher Wiley-Blackwell
Volume 22
Issue 2
First Page 1082
Last Page 1092
Language eng
Bibliographic Citation Tanner, K., Roy, N., Merrill, R. M., Sauder, C., Houtz, D. R., & Smith, M. E. (2012). Case-control study of risk factors for spasmodic dysphonia: a comparison with other voice disorders. Laryngoscope, 122(5), 1082-92.
Rights Management (c) Wiley-Blackwell The definitive version is available at www3.interscience.wiley.com ; This is the pre-peer reviewed version of the following article: Tanner, K., Roy, N., Merrill, R. M., Sauder, C., Houtz, D. R., & Smith, M. E. (2012). Case-control study of risk factors for spasmodic dysphonia: a comparison with other voice disorders. Laryngoscope, 122(5), 1082-92, which has been published in final form at DOI: 10.1002/lary.22471
Format Medium application/pdf
Format Extent 1,503,280 bytes
Identifier uspace,17615
ARK ark:/87278/s6417fws
Setname ir_uspace
Date Created 2013-05-22
Date Modified 2013-05-29
ID 708817
Reference URL https://collections.lib.utah.edu/ark:/87278/s6417fws
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