A 3D glass optrode array for optical neural stimulation

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Publication Type pre-print
School or College College of Engineering
Department Electrical & Computer Engineering
Creator Blair, Steven
Other Author Abaya, T. V. F.; Tathireddy, P.; Rieth, L.; Solzbacher, F.
Title A 3D glass optrode array for optical neural stimulation
Date 2012-01-01
Description This paper presents optical characterization of a first-generation SiO2 optrode array as a set of penetrating waveguides for both optogenetic and infrared (IR) neural stimulation. Fused silica and quartz discs of 3-mm thickness and 50-mm diameter were micromachined to yield 10×10 arrays of up to 2-mm long optrodes at a 400-mm pitch; array size, length and spacing may be varied along with the width and tip angle. Light delivery and loss mechanisms through these glass optrodes were characterized. Light in-coupling techniques include using optical fibers and collimated beams. Losses involve Fresnel reflection, coupling, scattering and total internal reflection in the tips. Transmission efficiency was constant in the visible and near-IR range, with the highest value measured as 71% using a 50-mm multi-mode in-coupling fiber butt-coupled to the backplane of the device. Transmittance and output beam profiles of optrodes with different geometries was investigated. Length and tip angle do not affect the amount of output power, but optrode width and tip angle influence the beam size and divergence independently. Finally, array insertion in tissue was performed to demonstrate its robustness for optical access in deep tissue.
Type Text
Publisher Optical Society of America
Volume 3
Issue 12
First Page 3087
Last Page 3104
Dissertation Institution University of Utah
Language eng
Bibliographic Citation Abaya, T. V. F., Blair, S., Tathireddy, P., Rieth, L., & Solzbacher, F. (2012). A 3D glass optrode array for optical neural stimulation. Biomedical Optics Express, 3(12), 3087-104.
Rights Management (c) Optical Society of America
Format Medium application/pdf
Format Extent 2,040,611 bytes
Identifier uspace,18142
ARK ark:/87278/s6rr2h1b
Setname ir_uspace
Date Created 2013-01-25
Date Modified 2013-01-25
ID 708299
Reference URL https://collections.lib.utah.edu/ark:/87278/s6rr2h1b
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