Cyclical magnetic field flow fractionation

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Publication Type Journal Article
School or College College of Engineering
Department Mechanical Engineering
Creator Gale, Bruce K.
Other Author Tasci, T. O.; Johnson, W. P.
Title Cyclical magnetic field flow fractionation
Date 2012-01-01
Description In this study, a new magnetic field flow fractionation (FFF) system was designed and modeled by using finite element simulations. Other than current magnetic FFF systems, which use static magnetic fields, our system uses cyclical magnetic fields. Results of the simulations show that our cyclical magnetic FFF system can be used effectively for the separation of magnetic nanoparticles. Cyclical magnetic FFF system is composed of a microfluidic channel (length¼5 cm, height¼30 lm) and 2 coils. Square wave currents of 1Hz (with 90 deg of phase difference) were applied to the coils. By using Comsol Multiphysics 3.5a, magnetic field profile and corresponding magnetic force exerted on the magnetite nanoparticles were calculated. The magnetic force data were exported from Comsol to Matlab. In Matlab, a parabolic flow profile with maximum flow speed of 0.4mL/h was defined. Particle trajectories were obtained by the calculation of the particle speeds resulted from both magnetic and hydrodynamic forces. Particle trajectories of the particles with sizes ranging from 10 to 50 nm were simulated and elution times of the particles were calculated. Results show that there is a significant difference between the elution times of the particles so that baseline separation of the particles can be obtained. In this work, it is shown that by the application of cyclical magnetic fields, the separation of magnetic nanoparticles can be done efficiently.
Type Text
Publisher American Institute of Physics (AIP)
Volume 111
Issue 7
First Page 07D128-1
Last Page 07D128-3
Dissertation Institution University of Utah
Language eng
Bibliographic Citation Tasci, T. O., Johnson, W. P., & Gale, B. K. (2012). Cyclical magnetic field flow fractionation. Journal of Applied Physics, 111(7), 07D128-1-07D128-3.
Rights Management (c)American Institute of Physics. The following article appeared in Tasci, T. O., Johnson, W. P., & Gale, B. K. Cyclical magnetic field flow fractionation. Journal of Applied Physics, 111(7), 2012 and may be found at (URL/link for published article abstract).
Format Medium application/pdf
Format Extent 801,188 bytes
Identifier uspace,17464
ARK ark:/87278/s6f486w3
Setname ir_uspace
Date Created 2012-08-01
Date Modified 2012-08-21
ID 707965
Reference URL https://collections.lib.utah.edu/ark:/87278/s6f486w3
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