Secret of life module: on the brink, four profiles in groundbreaking science
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Publication Type video
School or College School of Medicine; College of Science
Department Human Genetics; Oncological Sciences; Biology
Program Institute of Human Genetics. Howard Hughes Medical Institute.
Other Author WGBH
Title Secret of life module: on the brink, four profiles in groundbreaking science
Description This is a 15 minutes, 12 seconds segment of the WGBH series, Secret of life. Profiles include Dennis Slamon of UCLA and his work on the oncagenes and the creation of excess receptors that play a significant role in breast cancer; Patricia Steeg of the National Cancer Institute (NCI) and her work on the Nm23 gene and its role in breast cancer metastasis; Mary-Claire King of the University of Washington and her work locating the breast cancer gene, BRCA1; and Mario Capecchi of the University of Utah and his development of a stable process for creating transgenic mice and providing a way of creating non-human modules for studying human diseases. Other topics include some of the ethical issues involved in genetic research.
Type Image/MovingImage
Publisher WGBH
Subject Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Cancer - Research; Capecchi, Mario R.; Science - Moral and ethical aspects; Human chromosome abnormalities - Diagnosis; Gene expression; Gene regulation
Subject MESH Genetic Research; Gene Targeting; Mice, Knockout; DNA Mutational Analysis; Recombination, Genetic; Ethics, Medical; Gene Expression Regulation, Developmental
Language eng
Rights Management (c) WGBH
Identifier ir-main,1829
ARK ark:/87278/s60g43wr
Setname ir_uspace
ID 707896
Reference URL
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