Role of Hox genes in mediating the mammalian body plan
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Publication Type video
School or College School of Medicine; College of Science
Department Human Genetics; Oncological Sciences; Biology
Program Institute of Human Genetics. Howard Hughes Medical Institute.
Creator Capecchi, Mario R.
Title Role of Hox genes in mediating the mammalian body plan
Description This is a 1 hour, 5 minutes, 28 seconds video of a lecture given by Mario Capecchi on the genetic analysis of the Hox complex, or Hox cluster and their role in embryogenesis. Using examples such as the development of the hindbrain (rhombencephalon), facial nerves, and hands Capecchi outlines the relationship of the location of a specific gene on a chromosome and its expression, both where it is expressed and when. By knocking out specific genes, it is possible to trace the mutations that result and to infer the function of the gene.
Type Image/MovingImage
Publisher University of Utah
Subject Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Homeobox genes; Histology - Pathological; Gene expression; Gene regulation; Genotype; Phenotype
Subject MESH Genetic Research; Gene Targeting; Mice, Knockout; DNA Mutational Analysis; Recombination, Genetic; Ethics, Medical; Gene Expression Regulation, Developmental
Language eng
Rights Management (c) Mario R. Capecchi
Identifier ir-main,1826
ARK ark:/87278/s6vx117h
Setname ir_uspace
ID 707685
Reference URL
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