| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Physics |
| Creator |
Gerton, Jordan |
| Other Author |
Xie, Changan; Mu, Chun; Cox, Jonathan R. |
| Title |
Tip-enhanced fluorescence microscopy of high-density samples |
| Date |
2006 |
| Description |
High-density samples of fluorescent quantum dots (QDs) were imaged using an apertureless near-field optical microscopy technique. QD fluorescence was modulated by oscillating a silicon atomic force microscope tip above an illuminated sample and a lock-in amplifier was used to suppress background from the excitation laser. Spatial resolution near 10 nm and a peak signal-to-noise ratio (SNR) of ~60 were achieved. Individual QDs within high-density ensembles were still easily resolved (SNR>5) at a density of 14 QDs/µm2. These results have favorable implications for the eventual nanoscale imaging of viable biological systems, such as cellular membranes. |
| Type |
Text |
| Publisher |
American Institute of Physics (AIP) |
| Journal Title |
Applied Physics Letters |
| Volume |
89 |
| Issue |
14 |
| First Page |
143117 |
| DOI |
10.1063/1.2358122 |
| citatation_issn |
36951 |
| Language |
eng |
| Bibliographic Citation |
Xie, C., Mu, C., Cox, J. R., & Gerton, J. M. (2006). Tip-enhanced fluorescence microscopy of high-density samples. Applied Physics Letters, 89(14), 143117. |
| Rights Management |
(c)American Institute of Physics. The following article by Xie, C., Mu, C., Cox, J. R., & Gerton, J. M. appeared in Applied Physics Letters, 89(14) 2006 and may be found at (10.1063/1.2358122). |
| Format Medium |
application/pdf |
| Format Extent |
281,631 bytes |
| Identifier |
ir-main,11286 |
| ARK |
ark:/87278/s6s18m48 |
| Setname |
ir_uspace |
| ID |
707125 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6s18m48 |
