On the mechanism of the polynucleotide joining reaction

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Olivera, Baldomero M.
Other Author Hall, Zach W.; Anraku, Yasuhiro; Chien, Janice R.; Lehman, I. R.
Title On the mechanism of the polynucleotide joining reaction
Date 1968
Description Polynucleotide-joining enzymes (ligases) have been identified in uninfected and phage-infected Escherichia coli (Gellert, 1967; Olivera and Lehman, 1967a; Zimmerman et al., 1967; Gefter et al., 1967; Weiss and Richardson, 1967a; Cozzarelli et al., 1967). Both types of enzyme catalyze the synthesis of a phosphodiester bond between the 3' hydroxyl and 5' phosphoryl termini of DNA chains which have been properly aligned in a double-helical structure.
Type Text
Publisher Cold Spring Harbor Lab Press
Volume 33
First Page 27
Last Page 34
Subject Enzyme-AMP; Enzyme-Adenylate; DNA-Adenylate; Poly dt-Adenylate; Pyrophosphate bond
Subject LCSH Ligases; Nucleic acids; Escherichia coli
Language eng
Bibliographic Citation Olivera, B. M., Hall, Z. W., Anraku, Y., Chien, J. R., & Lehman, I. R. (1968). On the mechanism of the polynucleotide joining reaction. Cold Spring Harbor Symposia on Quantitative Biology, 33, 27-34.
Rights Management (c) Cold Spring Harbor Laboratory Press-CSHL Press
Format Medium application/pdf
Format Extent 4,299,342 bytes
Identifier ir-main,8150
ARK ark:/87278/s69z9phc
Setname ir_uspace
ID 707113
Reference URL https://collections.lib.utah.edu/ark:/87278/s69z9phc
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