Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease

Publication Type journal article
School or College School of Medicine
Department Neurosurgery
Creator Couldwell, William T.
Other Author Sutton, James P.; Lew, Mark F.; Mallory, Lou; Grafton, Scott; DeGiorgio, Christopher; Welsh, Mickie; Apuzzo, Michael L. J.; Ahmadi, Jamshid; Waters, Cheryl H.
Title Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease
Date 1995
Description IN A PRELIMINARY study, the effects of ventroposterior medial pallidotomy were evaluated in five patients with advanced Parkinson's disease in whom medical therapy had failed. The mean age was 67.0 ? 5.6 years, and t h e mean Hoelin and Yahr stage when "off" was 3.9 ? 1.3. Three patients received unilateral pallidotomies; two of these received another pallidotomy after 8 weeks. Two other patients received staged bilateral pallidotomies. No significant differences in overall function could be seen before and after the first surgical procedure. All three .patients with peak-dose dyskinesias or dystonia had marked contralateral reduction in these symptoms. Ventroposterior medial pallidotomy can ameliorate peak-dose dyskinesias in patients with advanced Parkinson's disease. Overall functional improvement is not remarkable.
Type Text
Publisher Wolters Kluwer (LWW)
Volume 36
Issue 6
First Page 1112
Last Page 1117
Subject Pallidotomy; Dyskinesia; Stereotaxy; Postoperative morbidity
Subject LCSH Parkinson's disease -- Treatment; Globus pallidus -- Surgery
Language eng
Bibliographic Citation Sutton, J. P., Couldwell, W., Lew, M. F., Mallory, L., Grafton, S., DeGiorgio, C., Welsh, M., Apuzzo, M. L. J., Ahmadi, J., & Waters, C. H. (1995). Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease. Neurosurgery 36(6), 1112-7.
Rights Management © Wolters Kluwer (LWW) http://lww.com
Format Medium application/pdf
Format Extent 1,109,570 bytes
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Reference URL https://collections.lib.utah.edu/ark:/87278/s6s760xf
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