Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Beckerle, Mary C.; Hoffman, Laura M.; Yoshigi, Masaaki
Other Author Jensen, Christopher C.; Kloeker, Susanne; Wang, C.-L. Albert
Title Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling
Date 2006
Description Focal adhesions are specialized regions of the cell surface where integrin receptors and associated proteins link the extracellular matrix to the actin cytoskeleton. To define the cellular role of the focal adhesion protein zyxin, we characterized the phenotype of fibroblasts in which the zyxin gene was deleted by homologous recombination.
Type Text
Publisher Rockefeller University Press
Volume 172
Issue 5
First Page 771
Last Page 782
Subject Zyxin; Actin; Mena/VASP
Subject LCSH Phosphoproteins; Cytoskeletal proteins; Protein-protein interactions; Cells -- Motility
Language eng
Bibliographic Citation Hoffman, L. M., Jensen, C. C., Kloeker, S., Wang, C.-L. A., Yoshigi, M., & Beckerle, M. C. (2006). Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling. Journal of Cell Biology, 172(5), 771-82.
Rights Management (c) Hoffman, L. M., Jensen, C. C., Kloeker, S., Wang, C.-L. A., Yoshigi, M., & Beckerle, M. C., 2006. Originally published in J. Cell Biol. 172(5), 771-82. http://creativecommons.org/licenses/by-nc-sa/3.0/
Format Medium application/pdf
Format Extent 2,472,790 bytes
Identifier ir-main,6611
ARK ark:/87278/s664079p
Setname ir_uspace
ID 706555
Reference URL https://collections.lib.utah.edu/ark:/87278/s664079p
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