Novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation

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Publication Type Journal Article
School or College College of Mines & Earth Sciences
Department Metallurgical Engineering
Creator Miller, Jan D.; Yost, Garold S.; Veranth, John M.
Other Author Deering, Cassandra E.; Tadjiki, Soheyl; Assemi, Shoeleh
Title Novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation
Date 2008
Description A novel methodology to detect unlabeled inorganic nanoparticles was experimentally demonstrated using a mixture of nano-sized (70 nm) and submicron (250 nm) silicon dioxide particles added to mammalian tissue. The size and concentration of environmentally relevant inorganic particles in a tissue sample can be determined by a procedure consisting of matrix digestion, particle recovery by centrifugation, size separation by sedimentation field-flow fractionation (SdFFF), and detection by light scattering.
Type Text
Publisher BioMed Central
Volume 5
Issue 18
First Page 1
Last Page 11
Subject Sedimentation field-flow fractionation; Transmission electron microscopy; Tissue digestion
Subject LCSH Nanoparticles -- Toxicology; Nanoparticles -- Health aspects
Language eng
Bibliographic Citation Deering, C. E., Tadjiki, S., Assemi, S., Miller, J. D., Yost, G. S., & Veranth, J. M. (2008). Novel method to detect unlabeled inorganic nanoparticles and submicron particles in tissue by sedimentation field-flow fractionation. Particle and Fibre Toxicology, 5(18), 1-11.
Rights Management (c) Cassandra E. Deering, Soheyl Tadjiki, Shoeleh Assemi, Jan D. Miller, Garold S. Yost, and John M. Veranth
Format Medium application/pdf
Format Extent 685,368 bytes
Identifier ir-main,7695
ARK ark:/87278/s6sq9hw5
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2013-02-20
ID 705823
Reference URL https://collections.lib.utah.edu/ark:/87278/s6sq9hw5
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