Does thalamotomy alter the course of Parkinson's disease?

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Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Kestle, John R. W.
Other Author Tasker, R. R.; DeCarvalho, G. C.; Li, C. S.
Title Does thalamotomy alter the course of Parkinson's disease?
Date 1996
Description Irving Cooper (3) observed that unilateral Parkinson's disease seemed less likely to progress to the other side of the body after thalamotomy that abolished contralateral tremor and rigidity, an effect that he felt might be the result of either the surgery itself or the slow progression of that particular patient's disease. In 1968, Scott et al. (16) reviewed 72 of Cooper's patients who had undergone thalamotomy for unilateral tremor and rigidity before 1963 and found that the disease had progressed to the opposite side in 33% of both the 39 with incomplete and the 33 with complete postoperative relief of contralateral tremor and rigidity. Matsumoto et al. (10) resurrected the notion that surgery might influence the progress of Parkinson's disease, reporting that 48.4% of 64 patients undergoing unilateral, and 63.6% of 22 undergoing bilateral thalamotomy between 1964 and 1969 did not progress after completion of surgery up to the time of their review in 1981, and Miyamoto et al. (11) reached similar conclusions.
Type Text
Publisher Wolters Kluwer (LWW)
First Page 563
Last Page 583
Subject LCSH Thalamotomy; Parkinson's disease
Language eng
Bibliographic Citation Tasker, R. R., DeCarvalho, G. C., Li, C. S., & Kestle, J. R. (1996). Does thalamotomy alter the course of Parkinsons disease? Advances in Neurology, 69, 563-83.
Rights Management © Wolters Kluwer (LWW)
Format Medium application/pdf
Format Extent 1,224,273 bytes
Identifier ir-main,13146
ARK ark:/87278/s6tq6jx6
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 704847
Reference URL