Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability

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Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Schmidt, Meic H.
Other Author Finn, Michael A.; McCall, Todd D.
Title Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability
Date 2007
Description PPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. The authors report the case of an 82-year-old woman who presented with long-standing neck pain and acute upper-extremity numbness and weakness. Computed tomography imaging revealed a mixed sclerotic and lucent lesion affecting the dens and right lateral mass of C-2. There was also a pathological fracture at the base of the dens with 8 mm of anterior dens displacement. Magnetic resonance imaging demonstrated a diffusely infiltrative process that was nonenhancing. Because of instability, the patient underwent transarticular screw fixation, and a biopsy of the lesion was also performed at this time. Histopathological analysis was consistent with a diagnosis of PVNS. To the authors' knowledge, this is the first report of PVNS involving the C-2 vertebra or causing a pathological fracture.
Type Text
Publisher American Association of Neurological Surgeons (AANS)
Volume 7
Issue 2
First Page 248
Last Page 253
Subject Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid
Subject LCSH Synovitis; Spine -- Wounds and injuries; Spine -- Surgery
Language eng
Bibliographic Citation Finn, M. A., McCall, T. D., & Schmidt, M. H. (2007). Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability. Case report and review of the literature. Journal of Neurosurgery: Spine, 7(2), 248-53.
Rights Management (c) American Association of Neurological Surgeons
Format Medium application/pdf
Format Extent 783,417 bytes
Identifier ir-main,12793
ARK ark:/87278/s6h99pj4
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 704481
Reference URL https://collections.lib.utah.edu/ark:/87278/s6h99pj4
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