Gene targeting. How efficient can you get?

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Publication Type Journal Article
School or College School of Medicine; College of Science
Department Oncological Sciences; Biology; Human Genetics
Program Institute of Human Genetics; Howard Hughes Medical Institute (HHMI)
Creator Capecchi, Mario R.
Title Gene targeting. How efficient can you get?
Date 1990-11-08
Description With targeting in Leishmania and Trypanosoma, there are now greater incentives to develop the technology in organisms of intermediate complexity such as Caenorhabditis elegans and Drosophila. The ratio of homologous to nonhomologus recombination in these organisms might prove to be greater than in mammalian cell, thereby helping in the application of gene targeting to certain kinds of genetic analysis.
Type Text
Publisher Nature Publishing Group
Volume 348
Issue 6297
Subject Animals; DNA Mutational Analysis; Recombination, Genetic
Subject MESH Genetic Engineering; Leishmania tropica; Trypanosoma brucei brucei
Language eng
Bibliographic Citation Nature. 1990 Nov 8;348(6297):109. Capecchi MR. Gene targeting. How efficient can you get? Retrieved on November 1 2006 from;jsessionid=002E7F1A070570371747BB6B3DF9E9FE.
Rights Management copyright ? 1990 Nature Publishing Group. All Rights Reserved.
Format Medium application/pdf
Identifier ir-main,533
ARK ark:/87278/s65h80h0
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 704180
Reference URL
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