| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Beckerle, Mary C. |
| Other Author |
Nix, David A.; Fradelizi, Julie; Bockholt, Susanne; Menichi, Bernadette; Louvard, Daniel; Friederich, Evelyne |
| Title |
Targeting of zyxin to sites of actin membrane interaction and to the nucleus |
| Date |
2001 |
| Description |
The localization of proteins to particular intracellular compartments often regulates their functions. Zyxin is a LIM protein found prominently at sites of cell adhesion, faintly in leading lamellipodia, and transiently in cell nuclei. Here we have performed a domain analysis to identify regions in zyxin that are responsible for targeting it to different subcellular locations. |
| Type |
Text |
| Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
| Volume |
276 |
| Issue |
37 |
| First Page |
34759 |
| Last Page |
34767 |
| Subject |
Zyxin; Actin; LIM domains; Focal adhesions; Lamellipodia; Cytoskeletal architecture |
| Subject LCSH |
Phosphoproteins; Cellular signal transduction; Cells -- Motility; Cell adhesion; Cell nuclei; Cells -- Morphology |
| Language |
eng |
| Bibliographic Citation |
Nix, D. A., Fradelizi, J., Bockholt, S., Menichi, B., Louvard, D., Friederich, E., & Beckerle, M. C. (2001). Targeting of zyxin to sites of actin membrane interaction and to the nucleus. Journal of Biological Chemistry, 276(37), 34759-67. |
| Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
| Format Medium |
application/pdf |
| Format Extent |
1,183,546 bytes |
| Identifier |
ir-main,6530 |
| ARK |
ark:/87278/s69c7fqj |
| Setname |
ir_uspace |
| ID |
703974 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s69c7fqj |
