Glioblastoma multiforme of the pineal region

Update item information
Publication Type Manuscript
School or College School of Medicine
Department Neurosurgery
Creator Couldwell, William T.; Schmidt, Richard H.; Salzman, Karen L.; Chin, Steven S.
Other Author Amini, Amin
Title Glioblastoma multiforme of the pineal region
Date 2006
Description Glioblastoma multiforme (GBMs) tumors are exceedingly rare tumors in the pineal region. We present three cases in which patients presented with a pineal/posterior third ventricular region mass and review all the previously reported cases in the literature. Pineal region GBM seems to be a very aggressive tumor with a high rate of leptomeningeal and ependymal metastatic disease. Patients usually present with signs and symptoms of hydrocephalus and Parinaud's syndrome. The clinical and radiological characteristics of pineal GBM do not differentiate it from other malignancies of this region, thus surgical biopsy is generally required for definitive diagnosis. Glioblastoma should be considered in the differential diagnosis of the pineal region tumors, especially when evidence of leptomeningeal or ependymal metastatic disease is present.
Type Text
Publisher Springer
Volume 79
Issue 3
First Page 1
Last Page 21
Subject Glioblastoma multiforme; Hydrocephalus; Leptomeningeal dissemination; Malignant glioma; Perinaud's syndrome; Pineal region; Spinal metastases
Subject LCSH Gliomas; Brain -- Cancer -- Diagnosis; Hydrocephalus; Brain -- Cancer -- Treatment
Subject MESH Brain Neoplasms
Language eng
Bibliographic Citation Amini, A., Schmidt, R. H., Salzman, K. L., Chin, S. S., & Couldwell, W. T. (2006). Glioblastoma multiforme of the pineal region. Journal of Neurooncology, 79(3), 307-14.
Rights Management (c) Springer (The original publication is available at
Format Medium application/pdf
Format Extent 2,057,735 bytes
Identifier ir-main,12635
ARK ark:/87278/s6tf0fkf
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-12-11
ID 703386
Reference URL
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