Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Ophthalmology; Neurosurgery; Neurology
Creator Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A.
Other Author Dalmau, Josep
Title Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.
Date 2006-07-11
Description A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-associated protein TIA-1 and the membranolytic protein granzyme-B. Although recovery was thought to be unlikely, treatment of the PNE with corticosteroids and resection of the associated lung cancer resulted in dramatic improvement for 21 months.
Type Text
Publisher Lippincott, Williams & Wilkins
Volume 67
Issue 1
First Page 146
Last Page 149
Subject Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex
Subject MESH Magnetic Resonance Imaging; Antibodies; Antigens; Encephalitis; Nerve Tissue Proteins
Language eng
Bibliographic Citation Blumenthal DT, Salzman KL, Digre KB, Jensen RL, Dunson WA, Dalmau J. Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis. Neurology. 2006 July 11. 67(1):146-9
Rights Management Copyright © Wolters Kluwer, Neurology, 67(1), 146-9, 2006
Format Medium application/pdf
Identifier ir-main,753
ARK ark:/87278/s6ng57v7
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 703249
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ng57v7
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