| Publication Type |
journal article |
| School or College |
School of Medicine |
| Department |
Ophthalmology |
| Creator |
Baehr, Wolfgang |
| Other Author |
Howes, Kimberly A.; Liu, Yang; Dunatef, Joshua L.; Milam, Ann; Frederick, Jeanne M.; Marks, Alexander |
| Title |
Receptors for advanced glycation end products as progressive factors in age-related macular degeneration |
| Date |
2004 |
| Description |
Advanced glycation end products (AGE) exacerbate disease progression through two general mechanisms: modifying molecules and forming nondegradable aggregates, thus impairing normal cellular/tissue functions, and altering cellular function directly through receptor-mediated activation. In the present study receptor for AGE (RAGE)-mediated cellular activation was evaluated in the etiology of human retinal aging and disease. |
| Type |
Text |
| Publisher |
Association for Research in Vision and Ophthalmology |
| Volume |
45 |
| Issue |
10 |
| First Page |
3713 |
| Last Page |
3720 |
| Subject |
Advanced glycation end products; AGE; receptor for AGE-mediated cellular activation; RAGE |
| Subject MESH |
Eye; Macular degeneration |
| Language |
eng |
| Bibliographic Citation |
Howes KA, Liu Y, Dunaief JL, Milam A, Frederick JM, Marks A, Baehr W. (2004). Receptors for advanced glycation end products as progressive factors in age-related macular degeneration. Invest Ophthalmol Vis Sci, 45(10), 3713-20 |
| Rights Management |
© Association for Research in Vision and Ophthalmology |
| Format Medium |
application/pdf |
| Identifier |
ir-main,248 |
| ARK |
ark:/87278/s6bk1whb |
| Setname |
ir_uspace |
| ID |
703144 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6bk1whb |
