| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael |
| Other Author |
Cartier, G. Edward; Yoshikami, Doju; Luo, Siqin |
| Title |
New α-conotoxin which targets α3ß2 nicotinic acetylcholine receptors |
| Date |
1996 |
| Description |
We have isolated a 16-amino acid peptide from the venom of the marine snail Conus magus which potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3ß2 subunits. This peptide, named a-conotoxin MII, was identified by electrophysiologically screening venom fractions against cloned nicotinic receptors expressed in Xenopus oocytes. |
| Type |
Text |
| Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
| Volume |
271 |
| Issue |
13 |
| First Page |
7522 |
| Last Page |
7528 |
| Subject |
Conotoxins; a-conotoxin MII; Conus magus |
| Subject LCSH |
Conus; Marine toxins; Nicotinic receptors -- Antagonists |
| Language |
eng |
| Bibliographic Citation |
Cartier, G. E., Yoshikami, D., Gray, W. R., Luo, S., Olivera, B. M., & McIntosh, J. M. (1996). New α-conotoxin which targets α3ß2 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 271(13), 7522-8. |
| Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
| Format Medium |
application/pdf |
| Format Extent |
200,677 bytes |
| Identifier |
ir-main,8349 |
| ARK |
ark:/87278/s6w09q2k |
| Setname |
ir_uspace |
| ID |
703048 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6w09q2k |
