| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Olivera, Baldomero M.; Gray, William Robert |
| Other Author |
Rivier, Jean E.; Galyean, Robert; Cruz, Lourdes J. |
| Title |
Conotoxin MI: disulfide bonding and conformational states |
| Date |
1983 |
| Description |
The toxic peptide from Conus magus venom (conotoxin MI) is a 14-amino acid peptide (McIntosh, M., Cruz, L. J., Hunkapiller, M. W., Gray, W. R., and Olivera, B. M. (1982) Arch. Biochem. Biophys. 218, 329-334) which inhibits the acetylcholine ceptor. In this work we have confirmed the primary structure and established the disulfide bonding configuration (Cys 3-Cys 8; Cys 4-Cys 14) by direct chemical synthesis of the toxin with specific disulfide bridges. |
| Type |
Text |
| Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
| First Page |
12247 |
| Last Page |
12251 |
| Subject |
Conotoxins; Disulfide bonding; Venom; Conus magus |
| Subject LCSH |
Neurotoxic agents; Neuropeptides; Conus |
| Language |
eng |
| Bibliographic Citation |
Gray, W. R., Rivier, J. E., Galyean, R., Cruz, L. J., & Olivera, B. M. (1983). Conotoxin MI: disulfide bonding and conformational states. Journal of Biological Chemistry, 258, 12247-51. |
| Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
| Format Medium |
application/pdf |
| Format Extent |
671,374 bytes |
| Identifier |
ir-main,8188 |
| ARK |
ark:/87278/s62v308g |
| Setname |
ir_uspace |
| ID |
703000 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62v308g |
