| Publication Type |
abstract |
| School or College |
School of Medicine |
| Department |
Pathology |
| Program |
ARUP Institute for Clinical and Experimental Pathology |
| Creator |
Vaughn, Cecily P.; Crockett, David K.; Lim, Megan S.; Elenitoba-Johnson, Kojo S.J. |
| Title |
Analytical characteristics of ICAT-LC-MS/MS for quantitative proteomics studies |
| Date |
2005-06-03 |
| Description |
Recent studies have employed isotope-coded affinity tags (ICAT) in concert with tandem mass spectrometry (MS/MS) to assess differential expression of proteins on a proteomic scale and perform unbiased quantitative comparisons between samples from different physiological or disease states. We sought to determine the performance characteristics and analytical profile of ICAT-based quantitative proteomics studies using proteins released by follicular lymphoma (FL)-derived cells as a model system. |
| Type |
Text |
| Publisher |
University of Utah, Associated and Regional University Pathologists (ARUP) Institute for Clinical and Experimental Pathology |
| Subject |
isotope-coded affinity tags; ICAT; mass spectrometry; MS/MS; proteomic scale; FL |
| Subject MESH |
Isotope Labeling; Proteins; Proteomics; Lymphoma, Follicular; Peptides |
| Language |
eng |
| Rights Management |
http://creativecommons.org/licenses/by-nc-nd/2.5/ |
| Format Medium |
application/pdf |
| Format Extent |
37,720 bytes |
| Identifier |
ir-main,134 |
| ARK |
ark:/87278/s6vt2975 |
| Setname |
ir_uspace |
| ID |
702902 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6vt2975 |
